2019
DOI: 10.1101/2019.12.19.882985
|View full text |Cite
Preprint
|
Sign up to set email alerts
|

Tuft cells restrain pancreatic tumorigenesis through paracrine eicosanoid signaling

Abstract: Despite numerous advances in our understanding of pancreatic ductal adenocarcinoma (PDA) genetics and biology, this disease is expected to become the second leading cause of cancer-related U.S. deaths within the next few years. Incomplete understanding of how it arises precludes development of early detection and interception strategies to improve therapeutic outcomes. Acinar to ductal metaplasia involving genesis of tuft cells is one early step in PDA formation, but their functional significance has remained … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Publication Types

Select...

Relationship

0
0

Authors

Journals

citations
Cited by 0 publications
references
References 73 publications
(88 reference statements)
0
0
0
Order By: Relevance

No citations

Set email alert for when this publication receives citations?