Tufted angioma

Silva, Camila Mendes da; Schettini, Antônio Pedro Mendes; Santos, Mônica; Chirano, Carlos Alberto

doi:10.1590/abd1806-4841.20175896

Cited by 4 publications

(3 citation statements)

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“…Its characteristic finding is tufts of capillaries located in the dermis in a "cannonball" pattern. 2 In our study, we collected the largest sample of tufted angioma from mainland China and presented comprehensive clinical and histopathological analysis.…”

Section: Discussionmentioning

confidence: 99%

“…4 Besides the common type of tufted angioma, the other type is Kasabach-Merritt phenomenon, which refers to tufted angioma complicated with thrombocytopenia and coagulation dysfunction. 2,7 The differential diagnoses of tufted angiomas are hemangioma-like lesions and vascular malformations, including infantile hemangioma, vascular malformations, angiosarcoma, Kaposiform hemangioendothelioma and Kaposi sarcoma in adults. 5,8 Histopathologic examination and immunohistochemistry are necessary to exclude other skin lesions.…”

Section: Discussionmentioning

confidence: 99%

“…Tufted angioma was first described by Sim-Davis et al in 1976. 1 The same condition was named as angioblastoma by Nakagawa in 1949 in Japanese literature 2 and as progressive capillary hemangioma by Macmillan and Champion. 3 Tufted angioma, characterized by tufts of endothelial cells in a cannonball pattern in the dermis, is a rare benign lesion with vascular proliferation.…”

Section: Introductionmentioning

confidence: 98%

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A retrospective study: Clinicopathological and immunohistochemical analysis of 54 cases of tufted angioma

Su¹,

Liu²,

Liu³

et al. 2020

Indian J Dermatol Venereol Leprol

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Background: Tufted angioma is a rare benign lesion with vascular proliferation. Aim: To retrospectively analyze the clinicopathological manifestations and immunohistochemical features of tufted angioma. Methods: Clinical and histopathological features of tufted angioma (n = 54) were evaluated and analyzed retrospectively in the Department of Dermatology, Xijing Hospital from 2003 to 2014. Results: Clinically, tufted angioma usually presented as erythematous plaques and papules on the head and neck (n = 11), trunk (n = 21) and extremities (n = 22), mainly in children (n = 48), without gender difference (24 males and 30 females). A total of 45 cases showed solitary lesions and nine cases showed multiple lesions. Common symptoms included pain (n = 11), tenderness (n = 7), itching (n = 1), hypertrichosis (n = 7), hyperhidrosis (n = 6) and Kasabach-Merritt phenomenon (n = 1). Histopathologically, typical tufted angioma (n = 37) showed proliferation of endothelial cells in a so-called cannonball pattern, while in the early (n = 4) and regressed (n = 13) stages the tufted appearance was not prominent. The proliferated endothelial cells were diffusely positive for CD31 and Wilms tumor 1, focally positive for D2-40 and Prox1, and negative for Glut-1. Limitations: Our research was confined to patients of Chinese origin and our sample size was limited. Conclusions: Tufted angioma is a rare vascular neoplasm with diverse clinical manifestations and unique pathological features. It should be recognized as a vascular tumor with lymphatic differentiation. We emphasize the importance of considering tufted angioma in the differential diagnoses of any congenital or acquired vascular tumor.

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Section: Discussionmentioning

confidence: 99%