Tulsi - Ocimum sanctum: A herb for all reasons

Cohen, Marc

doi:10.4103/0975-9476.146554

Cited by 351 publications

(206 citation statements)

References 69 publications

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“…Tulsi (Ocimum sanctum) was also found promising plant extracts for controlling sheath blight of rice. Tulsi is preeminent medicinal plant and scientific research is now confirming its beneficial effects (Cohen, 2014). Dheeba et al (2015) published that tulsi leaf extract is effective against early blight of tomato.…”

Section: Resultsmentioning

confidence: 99%

Effect of aqueous extracts of some indigenous medicinal plants on sheath blight of rice

Islam

Monjil

2016

J Bangladesh Agric Univ

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Aqueous extract of some indigenous plant parts were evaluated for its efficacy to control sheath blight of rice. Six treatments were applied, viz. T1-control (water spray), T2-Tulsi (Ocientific tenuiflorum) extract (1:10), T3-Nishinda (Vitex negundu) extract (1:10), T4-Thankuni (Centella asiatica) extracts (1:10), T5-Biskatali (Polygonum hydropiper) extract (1:10) and T6-Proud (Propiconazole @ 0.2%) as a positive control. Effect of these plant extracts on percent tiller infection and percent relative lesion height of sheath blight of rice cultivar BRRI dhan 49 was determined at 55, 75 and 95 day after transplanting (DAT). Number of infected tillers per hill differed significantly among the different treatments. The highest number of infected tillers was observed in control treatment. The lowest and statistically similar number of infected tillers was found in fungicide, Proud (Propiconazole)-and Biskatali-treated plots. Reduced number of infected tillers was observed in Tulsi, Thankuni and Nishinda. Highest percent tiller infection was recorded in control and lowest percent tiller infection was recorded in Proud and Biskatali, which were statistically similar. Nishinda, Tulsi and Thankuni had reduced tiller infection in compare to control. Percent reduction of tiller infection over control was achieved by proud followed by Biskatali. The highest lesion height was observed in control and lowest lesion height was found in Proud followed by Biskatali. The highest percent relative lesion height was recorded in control followed by Thankuni. The lowest percent relative lesion height was recorded in Proud preceded by Biskatali. Highest percent reduction of relative lesion height over control was achieved by proud followed by Biskatali. Thus, plant extracts of Biskatali, Tulsi, Nishinda and Thankuni are effective to control sheath blight of rice. Among the plant extracts, Biskatali showed highest control of sheath blight disease of rice.

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Section: Resultsmentioning

confidence: 99%

Effect of aqueous extracts of some indigenous medicinal plants on sheath blight of rice

Islam

Monjil

2016

J Bangladesh Agric Univ

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“…16,17 Accordingly, the protective action of Tulsi against stressinduced ulceration could be due to its histamine antagonistic, anticholinergic and antisecretory effects.…”

Section: Discussionmentioning

confidence: 99%

Activity of Tulsi leaves (Ocimum sanctum linn) in protecting gastric ulcer in rats by cold restrain method

Vaseem

Ali

Afshan

2017

Int J Basic Clin Pharmacol

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Background: Tulsi (Ocimum sanctum L.) common household plant, a potent adaptogen has been used for its medicinal property for many years. It is known in Ayurveda as Incomparable one, Mother of medicine of Nature and The Queen of Herbs. The present study evaluated the stress induced anti-ulcer effect of tulsi leaves in albino rats.Methods: Albino rats were randomly, allocated to different experimental groups and aqueous leaf extract of Tulsi (Ocimum sanctum) is given for 7 days. Gastric ulcers were induced by cold restrain methods and results were compared with control using distilled water and standard drug Ranitidine.Results: The Anti-ulcer effect of aqueous extract of Tulsi was significant in a dose dependent manner with cold restraint model. The percentage of ulcer protection of Tulsi leaf extract at dose 100mg/kg is 68.85% and at dose of 200mg/kg showed 65.66% and the standard drug Ranitidine showed 78.23% ulcer protection which is significant (p <0.05).Conclusions: The study showed that when Tulsi (Ocimum sanctum) is given at dose 100-200mg/kg for 7 days i.e., pre-treatment in rats for anti-ulcer effect, it caused a significant reduction in the ulcer scores and ulcer index when compared with control group, as evidenced by the gross appearance and histological findings of gastric mucosa in rats. There were few signs of mucosal injury and the percentage of damage was less compared to control group. Serosal surface revealed very few dilated blood vessels and petechial hemorrhages and mucosal surface had few ulcers of varying sizes.

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“…Research also suggests that Melissa officinalis exert protective activities in Ocimum sanctum, also known as 'Tulsi' in Hindi and 'Holy Basil' in English belongs to family Labiatae. The plant is also reported to contain alkaloids, glycosides, saponins, and tannins, vitamin C, and maleic acid, citric and tartaric acid [74]. A research conducted by the PC12 cell line and might protect neurons from oxidative stress [73].…”

Section: Melissa Officinalismentioning

confidence: 99%

Herbal Medicines as Neuroprotective Agent: A Mechanistic Approach

Roy

Awasthi

2017

Int J Pharm Pharm Sci

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Neurodegeneration refers to a condition of neuronal death occurring as a result of progressive disease of long-term and is becoming a major health problem in the 21st century. Neurons degenerated are not replaced resulting in a cognitive loss, many neurodegenerative disorders, such as schizophrenia, depression, Alzheimer's disease (AD), dementia, cerebrovascular impairment, seizure disorders, head injury, parkinsonism. The common pathology of neurodegeneration includes deposition of misfolded proteins such as amyloid-β (Aβ) in Alzheimer's disease, α-synuclein in Parkinson's disease (PD), transactive response DNA-binding protein 43 (TDP-43) in dementia. Neuroprotection refers to the strategies and possible mechanisms that are able to protect the central nervous system (CNS) against neuronal injury and neurodegenerative disorders. The past decade has witnessed an intense interest in herbal plants having long-term health-promoting or medicinal qualities. Comprehensive research and discovery have demonstrated that natural products, medicinal herbs, plant extracts, and their metabolites, have great potential as the neuroprotective agent. Although the precise mechanisms of action of herbal drugs have yet to be determined, some of them have been shown to prevent formation of betaamyloid plaques, promote nerve growth, some inhibit acetylcholinesterase (AChE) enzyme and malondialdehyde (MDA) formation in brain while other exhibits antioxidant activity by increasing the level of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx). Thus the herbal plants can be a valuable source of the drug against neurodegenerative disorders which will require high-throughput screening. This review will highlight the role of herbal plants and their phytoconstituents against neurodegenerative diseases and other related disorders, focusing on their mechanism of action and therapeutic potential.

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Tulsi - Ocimum sanctum: A herb for all reasons

Cited by 351 publications

References 69 publications

Effect of aqueous extracts of some indigenous medicinal plants on sheath blight of rice

Effect of aqueous extracts of some indigenous medicinal plants on sheath blight of rice

Activity of Tulsi leaves (Ocimum sanctum linn) in protecting gastric ulcer in rats by cold restrain method

Herbal Medicines as Neuroprotective Agent: A Mechanistic Approach

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