Tumeurs testiculaires : les enjeux diagnostiques de l’imagerie

Rocher, Laurence; Ksouri, Aida; Maxwell, Florian; Bresson, B.; Hindawi, Ghina; Balasa, Cristina; Albigès, Laurence

doi:10.1016/j.bulcan.2019.03.008

Cited by 5 publications

(1 citation statement)

References 36 publications

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“…Choriocarcinoma is the rarest tumor but most aggressive GCT, with a high frequency of lung or brain metastases and elevated BHCG levels. On imaging, a typical pattern of malignancy is an inhomogeneous, not-well-described intra-testicular mass containing solid and cystic components, with increased internal blood flow [41] (Figure 4). Surgical excision of the tumor is the first step in treatment.…”

Section: Mixed Non-seminomatous Malignant Gctsmentioning

confidence: 99%

Imaging of Pediatric Testicular and Para-Testicular Tumors: A Pictural Review

Hermann

L’Herminé-Coulomb

Irtan

et al. 2022

Cancers

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Pre- and post-pubertal testicular tumors are two distinct entities in terms of epidemiology, diagnosis and treatment. Most pre-pubertal tumors are benign; the most frequent are teratomas, and the most common malignant tumors are yolk-sac tumors. Post-pubertal tumors are similar to those found in adults and are more likely to be malignant. Imaging plays a pivotal role in the diagnosis, staging and follow-up. The appearance on ultrasonography (US) is especially helpful to differentiate benign lesions that could be candidates for testis-sparing surgery from malignant ones that require radical orchidectomy. Some specific imaging patterns are described for benign lesions: epidermoid cysts, mature cystic teratomas and Leydig-cell tumors. Benign tumors tend to be well-circumscribed, with decreased Doppler flow on US, but malignancy should be suspected when US shows an inhomogeneous, not-well-described lesion with internal blood flow. Imaging features should always be interpreted in combination with clinical and biological data including serum levels of tumor markers and even intra-operative frozen sections in case of conservative surgery to raise any concerns of malignity. This review provides an overview of imaging features of the most frequent testicular and para-testicular tumor types in children and the value of imaging in disease staging and monitoring children with testicular tumors or risk factors for testicular tumors.

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Section: Mixed Non-seminomatous Malignant Gctsmentioning

confidence: 99%

Imaging of Pediatric Testicular and Para-Testicular Tumors: A Pictural Review

Hermann

L’Herminé-Coulomb

Irtan

et al. 2022

Cancers

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Tumores no germinales del testículo

Ferretti,

Cousin,

Alaghbari

et al. 2024

EMC - Urología

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Radiological features characterising indeterminate testes masses: a systematic review and meta‐analysis

et al. 2022

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The use of scrotal ultrasonography (SUS) has increased the detection rate of indeterminate testicular masses. Defining radiological characteristics that identify malignancy may reduce the number of men undergoing unnecessary radical orchidectomy. ObjectiveTo define which SUS or scrotal magnetic resonance imaging (MRI) characteristics can predict benign or malignant disease in pre-or post-pubertal males with indeterminate testicular masses. Evidence AcquisitionThis systematic review was conducted in accordance with Cochrane Collaboration guidance. Medline, Embase, Cochrane controlled trials and systematic reviews databases were searched from (1970( to 26 March 2021. Benign and malignant masses were classified using the reported reference test: i.e., histopathology, or 12 months progression-free radiological surveillance. Risk of bias was assessed using the Quality Assessment of Diagnostic Accuracy Studies-2 tool (QUADAS-2). Evidence SynthesisA total of 32 studies were identified, including 1692 masses of which 28 studies and 1550 masses reported SUS features, four studies and 142 masses reported MRI features. Meta-analysis of different SUS (B-mode) values in post-pubertal men demonstrated that a size of ≤0.5 cm had a significantly lower odds ratio (OR) of malignancy compared to masses of >0.5 cm (P < 0.001). Comparison of masses of 0.6-1.0 cm and masses of >1.5 cm also demonstrated a significantly lower OR of malignancy (P = 0.04). There was no significant difference between masses of 0.6-1.0 and 1.1-1.5 cm. SUS in postpubertal men also had a statistically significantly lower OR of malignancy for heterogenous masses vs homogenous masses (P = 0.04), hyperechogenic vs hypoechogenic masses (P < 0.01), normal vs increased enhancement (P < 0.01), and peripheral vs central vascularity (P < 0.01), respectively. There were limited data on pre-pubertal SUS, pre-pubertal MRI and post-pubertal MRI. ConclusionsThis meta-analysis identifies radiological characteristics that have a lower OR of malignancy and may be of value in the management of the indeterminate testis mass.

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Tumeurs testiculaires : les enjeux diagnostiques de l’imagerie

Cited by 5 publications

References 36 publications

Imaging of Pediatric Testicular and Para-Testicular Tumors: A Pictural Review

Imaging of Pediatric Testicular and Para-Testicular Tumors: A Pictural Review

Tumores no germinales del testículo

Radiological features characterising indeterminate testes masses: a systematic review and meta‐analysis

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