Tumor del seno endodérmico primario de pulmón. Una rara entidad anatomopatológica

Gil, María Elena Ramírez; Vallina, Primitivo Martínez; Muñoz, Patricia Menal; Ferrández, Jorge Hernández; González, Guillermo Muñoz; Andrés, Juan José Rivas de

doi:10.1016/j.arbres.2010.03.007

Cited by 3 publications

(1 citation statement)

References 5 publications

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“…Some clinical conditions are associated with yolk sac tumor, according to literature, such as Klinefelter syndrome (around 20% of cases), precocity of pubertal development and hematological neoplasia, such as leukemia and myelodysplastic syndrome. 2 , 8 , 9 …”

Section: Discussionmentioning

confidence: 99%

Yolk sac primary tumor of mediastino: a rare case in a young adult

Silva

Vergílio

Yamaguti

et al. 2017

Einstein (São Paulo)

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Germ cell tumors are rare neoplasms that mostly occur in the gonads, although they can also affect other body sites, especially the anterior mediastinum (50 to 70% of all extragonadal germ cell tumors). We report a case of a primary mediastinal yolk sac tumor, a rare and aggressive germ cell tumors subtype. This was a 38-year-old man who was admitted to Hospital do Servidor Público Estadual “Francisco Morato de Oliveira”, complaining about dyspnea and dry cough for 1 year. The computed tomography scan of his chest revealed a large mass in the anterior mediastinum with heterogeneous enhancement to the contrast associated with pleural effusion. There were also high serum levels of alpha-fetoprotein. After neoadjuvant chemotherapy, the patient underwent surgical resection of the mass, followed by pathological examination, which confirmed a primary mediastinal yolk sac tumor, a nonseminomatous subtype of germ cell tumors. Primary mediastinal yolk sac tumors have poor prognosis, despite advances in therapy with surgical resection and cisplatin-based chemotherapy. This poor prognosis is due to the degree of invasion and unresectability in most patients by the time of the diagnosis.

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Section: Discussionmentioning

confidence: 99%

Yolk sac primary tumor of mediastino: a rare case in a young adult

Silva

Vergílio

Yamaguti

et al. 2017

Einstein (São Paulo)

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Germ Cell Tumors of Miscellaneous Extragonadal Sites

Rubio-Fernández

Retamero

Nogales

2017

Pathology and Biology of Human Germ Cell Tumors

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Primary endodermal sinus tumor originating from the sacral ligament: a case report and review of the literature

Han

Jia

Tang

et al. 2023

BMC Pregnancy Childbirth

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Background Endodermal sinus tumor (EST) is a malignant tumor originating from the ovary or testis. In most case, ultrasound examination shows ovarian mass. But there is a special kind of extra-gonadal endodermal sinus tumor, which occur in organs other than gonads with insidious onset. Here we reported a case of endodermal sinus tumor, which originated from the sacral ligament presenting as an acute lower abdominal pain. Case presentation A 14-year-old girl was admitted to the hospital because of acute lower abdominal pain. The ultrasound showed a mass with 72 mm × 64 mm × 50 mm in Douglas, and there was no abnormality in bilateral ovaries and fallopian tubes. Laparoscopic exploration showed a large amount of blood clots in the pelvic cavity. After removal of the blood, we found rotten fish-like tissue in the left sacral ligament, rapid pathology suggested endodermal sinus tumor. After the operation, we retrospectively examined the value of alpha-fetoprotein (AFP), which was found to be elevated, and post-operative paraffin pathology confirmed the diagnosis. After four cycles of BEP chemotherapy, exploratory laparotomy was performed to remove the visible lesion, but postoperative pathology showed no abnormality. At the one-year follow-up, the patient remained recurrence-free. Conclusion Extra-gonadal germ cell tumors are rarely reported. When young teenagers complain of acute lower abdominal pain with elevated AFP, but there was no lesion in bilateral ovaries and fallopian tubes, we must think about the possibility of endodermal sinus tumors. Accurate diagnosis facilitates complete resection of lesions and improves patient’s outcomes.

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Tumor del seno endodérmico primario de pulmón. Una rara entidad anatomopatológica

Cited by 3 publications

References 5 publications

Yolk sac primary tumor of mediastino: a rare case in a young adult

Yolk sac primary tumor of mediastino: a rare case in a young adult

Germ Cell Tumors of Miscellaneous Extragonadal Sites

Primary endodermal sinus tumor originating from the sacral ligament: a case report and review of the literature

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