Tumor fibroso solitario de la próstata

Non-epithelial prostatic neoplasms are infrequent and cover a broad array of entities that include both benign and highly aggressive tumours. Because they are very infrequent, there is often limited understanding of them, and the recognition of these entities, when encountered, may pose a diagnostic challenge, owing to histological overlap between them or their rarity. Most lesions in this category are mesenchymal in origin, such as prostatic stromal tumours arising from specialized prostatic stroma, smooth muscle tumours, both benign and malignant, and solitary fibrous tumours. Less commonly occurring tumours include neural, germ cell and melanocytic tumours that may be derived from cells not normally present in the prostate. Some tumours have well-established extraprostatic counterparts and, when encountered, are more commonly extraprostatic/secondary in origin; these include gastrointestinal stromal tumours and most haematopoietic tumours. The majority of tumours are characterized by a spindle cell pattern with significant overlap in morphological features. In this setting, appropriate use of immunohistochemistry and molecular studies are often necessary for accurate diagnosis, prognosis, or prediction for therapy. This review addresses and updates the clinicopathological features of the entire spectrum of non-epithelial tumours with an approach to the histological diagnosis.

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Tumor fibroso solitario inguinal maligno: Aportación de un caso

Abad

Peso

Fernández

et al. 2007

Arch. Esp. Urol.

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INTRODUCCIÓNEl Tumor Fibroso Solitario (TFS) es una neoplasia fusocelular poco frecuente, que posiblemente deriva de fibroblastos y células mesenquimales (1).Fue inicialmente descrito en la pleura en 1931 por Klemperer y Rabin (2) y durante mucho tiempo se consideró ésta su única localización. A lo largo de la historia el TFS ha recibido múltiples denominaciones: mesotelioma fibroso, tumor fibroso localizado, mesotelioma localizado, fibroma pleural. En la actualidad se han descrito múltiples casos de TFS en otras localizaciones.Se trata de un tumor de tamaño variable con un patrón histológico atípico (alternancia hiper e hipocelular con arquitectura vascular hemangiopericitoide en la mayoría de los casos) y positividad inmunohistoquímica en más del 90% para CD34.Las lesiones suelen ser asintomáticas y su diagnóstico incidental en la mayoría de casos. Su comportamiento es generalmente benigno. Aproximadamente un 10% de los casos de TFS extratorácico pueden recurrir localmente o a distancia (3). Todavía permanecen en controversia los factores que predicen su comportamiento maligno. Abad, A. Coloma Del Peso, L. M. Herranz Fernández y cols. P. Garrido

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Tumor fibroso solitario de la próstata

Cited by 3 publications

References 13 publications

Solitary fibrous tumor of the prostate

Solitary fibrous tumor of the prostate

Non‐epithelial neoplasms of the prostate

Tumor fibroso solitario inguinal maligno: Aportación de un caso

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