2021
DOI: 10.3390/cancers13020314
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Tumor Metabolome: Therapeutic Opportunities Targeting Cancer Metabolic Reprogramming

Abstract: The study of cancer metabolism is regaining center stage and becoming a hot topic in tumor biology and clinical research, after a period where such kind of experimental approaches were somehow forgotten or disregarded in favor of powerful functional genomic and proteomic studies [...]

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Cited by 3 publications
(1 citation statement)
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“…In recent years, metabolic phenotyping has become a powerful approach for the identification of new molecular biomarkers and metabolic vulnerabilities that could represent novel therapeutic opportunities in oncological diseases [13][14][15][16][17][18]. Hence, several metabolomics analyses have been carried out on PCa samples (e.g., tissue, urine, serum, plasma, and seminal fluid) to characterize the specific metabolic profile associated with PCa progression and identify metabolic alterations that may potentially be used as clinical biomarkers (reviewed in [19][20][21][22]).…”
Section: Introductionmentioning
confidence: 99%
“…In recent years, metabolic phenotyping has become a powerful approach for the identification of new molecular biomarkers and metabolic vulnerabilities that could represent novel therapeutic opportunities in oncological diseases [13][14][15][16][17][18]. Hence, several metabolomics analyses have been carried out on PCa samples (e.g., tissue, urine, serum, plasma, and seminal fluid) to characterize the specific metabolic profile associated with PCa progression and identify metabolic alterations that may potentially be used as clinical biomarkers (reviewed in [19][20][21][22]).…”
Section: Introductionmentioning
confidence: 99%