2024
DOI: 10.1186/s12964-024-01884-4
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Tumor-microenvironment-on-a-chip: the construction and application

Hanzheng Xu,
Jiangtao Wen,
Jiahua Yang
et al.

Abstract: Currently, despite the vast amounts of time and money invested in cancer treatment, cancer remains one of the primary threats to human life. The primary factor contributing to the low treatment efficacy is cancer heterogeneity. The unclear molecular mechanisms underlying tumorigenesis, coupled with the complexity of human physiology, and the inability of animal models to accurately replicate the human tumor microenvironment, pose significant hurdles in the development of novel cancer therapies. Tumor-microenvi… Show more

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