Tumor-targeted molybdenum disulfide@barium titanate core–shell nanomedicine for dual photothermal and chemotherapy of triple-negative breast cancer cells

Abstract

Combinational therapy can improve cancer treatment effectiveness by overcoming individual therapy shortcomings, leading to accelerated cancer cell apoptosis. The combinational cancer therapy attains by a single nanosystem with multiple physicochemical...

Micronutrient Status and Breast Cancer: A Narrative Review

“…A recent report indicated the possibility of using Mo compounds in the formation of anticancer drug carriers for breast cancer [182]. Molybdenum disulfide (MoS 2 ) and barium titanate (BT) core-shell nanoparticles (MoS 2 @BT CSNPs) can be used as a photothermal agent and drug carrier for the synergistic therapy (combining chemotherapy and hyperthermia) of breast cancer [182]. A nanocomposite named MoS 2 @BT-PDA-FA (MBPF) was synthesized using polydopamine and folic acid [182].…”

“…Molybdenum disulfide (MoS 2 ) and barium titanate (BT) core-shell nanoparticles (MoS 2 @BT CSNPs) can be used as a photothermal agent and drug carrier for the synergistic therapy (combining chemotherapy and hyperthermia) of breast cancer [182]. A nanocomposite named MoS 2 @BT-PDA-FA (MBPF) was synthesized using polydopamine and folic acid [182]. Inside the particle, gemcitabine was placed, giving a nano-drug which showed antitumor efficacy against TNBC cells [182].…”

“…A nanocomposite named MoS 2 @BT-PDA-FA (MBPF) was synthesized using polydopamine and folic acid [182]. Inside the particle, gemcitabine was placed, giving a nano-drug which showed antitumor efficacy against TNBC cells [182].…”

A copper–platinum nanoplatform for synergistic photothermal and chemodynamic tumor therapy via ROS outburst and GSH exhaustion

“…Photothermal therapy (PTT) has recently attracted widespread interest as a promising treatment option. [22][23][24] This method usually utilizes a photothermal agent (PTA) under near-infrared (NIR) laser irradiation to produce local hyperthermia, effectively eradicating tumors in a non-invasive manner with few side effects. However, dispersed hyperpyrexia damage to the adjacent tissues limits the application of PTT on tumors around vital organs.…”

Fabricating a PDA-Liposome Dual-Film Coated Hollow Mesoporous Silica Nanoplatform for Chemo-Photothermal Synergistic Antitumor Therapy

“…cannot achieve the ideal effect of tumor suppression. To overcome the limited therapeutic effect of single chemotherapy, the synergistic treatment of tumors by combining multiple antitumor strategies has attracted increasing attention [2][3][4][5][6][7][8]. More importantly, nanotechnology can enable multimodal synergistic therapies by assembling various therapeutic elements into a nanoplatform, thereby forming multifunctional nanomaterials [9][10][11].…”