Tumor virilizante de células esteroideas del ovario

Hernández, Rita Vidal; Arca, Silvia Campos; Rodríguez, M. Vázquez; Vázquez, Ovidio Vidal; Silva, Emilio Salvador Cabo

doi:10.1016/j.pog.2011.10.004

Cited by 2 publications

(1 citation statement)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, the left ovary neoplasia that was suspected before surgery was also identified; microscopically, the tumour presented features leading to the diagnosis of ovarian steroid cell tumour, NOS; diagnosis was also supported by the diffuse positivity for inhibin and calretinin 6 20 21. The absence of crystals of Reinke allows for differential diagnosis with Leydig cell tumour and the hilar localisation with stromal luteoma 22 23…”

Section: Discussionmentioning

confidence: 98%

Ovarian steroid cell tumour inducing virilisation in a postmenopausal woman

Pinto

Martins²,

Oliveira³

et al. 2022

BMJ Case Rep

View full text Add to dashboard Cite

Hyperandrogenism with virilisation de novo in postmenopausal women is exceedingly rare, with aetiology oscillating between ovarian tumours, adrenal tumours, ovarian hyperthecosis and, less frequently, Cushing’s syndrome. We report a case of a postmenopausal woman in her late 60s, referred from her primary healthcare physician to a gynaecology appointment due to hirsutism and vasomotor symptoms. At physical examination, clitoromegaly was also identified. Blood tests revealed severe hyperandrogenemia, with total testosterone above 200 ng/dL, but transvaginal ultrasound and abdominal CT were unremarkable. Three months later, abdominal CT was repeated, revealing a moderate heterogeneous enhancement with 18 mm on the left ovary, which was confirmed by transvaginal ultrasound. Total laparoscopic hysterectomy with bilateral adnexectomy was performed. Histopathological examination reported an ovarian steroid cell tumour not otherwise specified on the left ovary and bilateral ovarian hyperthecosis. Two months later, the patient had normal total testosterone and the hirsutism complaints were completely absent.

show abstract

Section: Discussionmentioning

confidence: 98%