Tumores de la conjuntiva

Saornil, María A.; Becerra, Emiliano M.; Mendez, MC; Blanco, Gonzalo

doi:10.4321/s0365-66912009000100003

Cited by 39 publications

(28 citation statements)

References 37 publications

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“…They noted two out of nine SCC cases HIV positive whereas in our study none of the case of SCC was HIV positive. Lee SB et al (2000) and Saronil MA et al (2009) have stated infection by HIV virus to be amongst a known predisposing factor for SCC.…”

Section: Discussionmentioning

confidence: 99%

Conjunctival Lesions: When Should We Perform Biopsy?

2018

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Introduction: The conjunctiva is a thin and flexible mucus membrane that provides a protective barrier for the eye. Very few histopathologic studies have been conducted on biopsies from conjunctival lesions (CL) in central India. Objective: To study the spectrum of CL and define those lesions that need attention with regard to need of biopsy in order to prevent grave sequelae and ocular morbidity. Results: Degenerative conditions such as pterygium followed by pinguicula were the commonest lesions seen in conjunctiva. Out of 129 subjects, youngest in the series was 3 years old while oldest patient was 72 years of age. Commonest age interval for involvement was 35 to 50 years. In children below 8 years, cystic lesions (infective or inclusion), limbal dermoid and choristoma were seen. Vascular lesions were noticed by patients for the first time between mid-teens to 25 years age. Premalignant lesions were dysplasia, actinic keratosis and PAM with or without XP. Malignant lesions in this series were squamous cell carcinoma, basal cell carcinoma and sebaceous carcinoma; which were observed in the age interval 25 to 75 years. In none of the malignant conditions there was deeper penetration into the globe or orbit. Though diagnosed within two weeks duration (by incisional biopsy) from appearance of nodule, unfavourable outcome was seen only in one malignant CL; a case having sebaceous carcinoma. In all pediatric cases outcome was good, except in child having choristoma, where amblyopia ensued before a diagnosis was made. Response to sclerotherapy was excellent as all the epibulbar vascular malformations regressed. All degenerative lesions regressed except one recurrence in a recurred pterygium. Case diagnosed as large B cell lymphoma recurred after one year. Dysplastic changes were seen to occur at limbus on followup in one XP, but in all cases of naevi, neither cellular atypia was seen nor melanoma developed. Conclusion: An overview of various CL disclosed that clinician has to differentiate benign from premalignant and malignant lesions. Early diagnosis, proper histological study and patient education, all are equally important for achieving good outcome.

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Section: Discussionmentioning

confidence: 99%

Conjunctival Lesions: When Should We Perform Biopsy?

2018

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“…The follow-up protocol after each session included measurement of visual acuity and intraocular pressure, Schirmer test and tear film breakup time, and biomicroscopy studies with seried photographs, which showed progressive regression of the tumor (Figs. 3,4,5). During the radiotherapy period and until 1 month later, the patient received topical anti-inflammatory diclofenac, eyedrops, and artificial tears.…”

Section: Case Reportmentioning

confidence: 94%

“…It is the most common type of ocular surface neoplasm, usually appearing in older patients, predominantly men. 2,3 The main risk factors associated with CCIN are infection by human papilloma virus or human immunodeficiency virus and exposure to ultraviolet rays. The most widely used treatment is complete resection, with or without adjuvant treatments such as cryotherapy, topical chemotherapy with mitomycin C, 5-fluorouracil, or interferon alpha-2b.…”

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confidence: 99%

Conjunctival–Corneal Intraepithelial Neoplasia (Bowen Disease) Treated With Orthovoltage

Sánchez-Pérez

Fuentes-Sánchez

Acosta-Acosta

2011

Cornea

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“…A review of the 360 cases of conjunctival tumors diagnosed at the Ocular Oncology Unit of the Valladolid University Hospital revealed that 124 (39.6%) were of epithelial origin and only 11 were malignant CSCC [4]. This is the first case of recurrence and intraocular invasion treated with enucleation of the eye.…”

Section: Discussionmentioning

confidence: 99%

Infiltrative Intraocular Conjunctival Squamous Cell Carcinoma after Local Resection and Brachytherapy: Clinical and Pathological Findings

et al. 2017

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A pseudophakic 70-year-old man presented to the clinic with a slow-growing conjunctival mass in the left eye. He was diagnosed with a conjunctival exophytic lesion suspicious of invasive conjunctival squamous cell carcinoma (CSCC). Excisional biopsy showed a well-differentiated CSCC with positive margins and the patient underwent adjuvant brachytherapy. Six weeks later, examination of the anterior segment revealed cells in the anterior chamber and a neurotrophic corneal ulcer with corneal perforation. Considering the high suspicion of intraocular invasion of CSCC, the left eye was enucleated. Histopathologic findings showed scarring of the ciliary body with fibrosis temporally. Nasally, the sclera showed a lobular infiltration of well-differentiated squamous carcinoma. The central cornea exhibited a large ulcer with perforation and infiltrating squamous cells adhering to the posterior surface. To our knowledge, this is the first documented case of an intraocular diffuse recurrence of CSCC after resection and adjuvant brachytherapy, with clinicopathologic correlation of radiation effects on the ocular tissues.

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Tumores de la conjuntiva

Cited by 39 publications

References 37 publications

Conjunctival Lesions: When Should We Perform Biopsy?

Conjunctival Lesions: When Should We Perform Biopsy?

Conjunctival–Corneal Intraepithelial Neoplasia (Bowen Disease) Treated With Orthovoltage

Infiltrative Intraocular Conjunctival Squamous Cell Carcinoma after Local Resection and Brachytherapy: Clinical and Pathological Findings

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