Tumores malignos del apéndice cecal en pacientes operados por apendicitis en la IV Región de Chile

Abstract

Malignant appendicular tumors on patients operated for acute appendicitisBackground: The most common malignant appendicular neoplasm is the neuroendocrine welldifferentiated tumor (NET). Other malignant tumors are uncommon, reported with a frequency of 0.2% of all appendectomies. Aim: To describe the characteristics of appendiceal malignant tumors found in regional hospitals of Northern Chile. Material and Methods: All patients operated for acute appendicitis between 2005 and 2011, in which a malignant appendiceal tumor was found in the pathological study, were analyzed. Clinical and survival information was obtained from medical records and national death registries. Results: We analyzed 8.972 appendectomy records. Appendicular tumors were found in 40 patients (0.4%). Thirty patients (0.3%) had malignant tumors. NET was the most common tumor found in 19 patients (63%). The tumor was smaller than 1 cm in 16 cases (53%). In 5 patients (17%), the tumor was larger than 2 cm with the appendicular base infiltrated by malignant cells. Most patients (83%) presented with stage I tumors. In 23 patients (77%), the appendectomy was considered sufficient and definitive treatment. Conclusions: In this series of patients, appendicular tumors had similar characteristics to those reported abroad. All patients had a favorable evolution without associated mortality or tumor relapse.

Tumor neuroendocrino, mucocele y adenoma tubulo-velloso: tres lesiones infrecuentes en el apéndice cecal

“…Su diagnóstico requiere un seguimiento de forma periódica mediante colonoscopias (Flórez et al, 2014). En algunos casos excepcionales, el diagnóstico de un tumor apendicular se sospecha durante la cirugía o en el período preoperatorio (Beltrán et al, 2013).…”

Neoplasias Malignas Primarias Del Apéndice Cecal: Estudio Comparativo Entre 2 Hospitales Regionales

“…La tendencia en nuestro estudio no varió respecto a la literatura, predominando el nET con un 87% en el HRA y con un 80% en el HRV, destacando una mayor incidencia en relación a cuatro series nacionales 5,18,19,21 (Tabla 4). Se encontró un Linfoma no Hodgkin en cada centro hospitalario, siendo éste una rareza en la literatura existente 22,23 .…”

“…En cuanto a las características del tumor, su ubicación más habitual es en la región distal, al igual que en nuestra serie y en las series nacionales existentes 5,18,19,21 . Esto es importante para determinar la conducta y el tratamiento del paciente 25 La conducta quirúrgica en las neoplasias del apéndice cecal son bastantes contradictorias y aún no existe acuerdo que permita orientar al cirujano sobre cuál es el tratamiento ideal 18 .…”

Incidence of Appendiceal Neoplasms in Appendectomy Patients

“…Tumors of the appendix are unusual entities, mainly diagnosed incidentally in the anatomopathological study of appendectomy pieces, and rarely suspected before or during a surgical procedure (5)(6)(7)(10)(11)(12)(13)(14). Therefore, the study of the appendiceal sample is crucial both to diagnose the presence of neoplasms, as well as to determine their histological subtype (4,9,11,14).…”

“…Its incidence is low but has increased as reported by different international series (8-10). Worldwide, it varies between 0,2% and 2,5% (5,10,24) (between 0,07% and 0,8% in Chile (10), 0,78% in Turkey ( 14), 0,9% in Spain (17), between 0,9% and 1,7% in the United States (6), 1,24% in Finland (5), 2,3% in Japan (8), and < 3% in Tunisia ( 15)). In Colombia, the incidence of tumors of the appendix is unknown.…”