Tumormarker und Immunszintigraphie in der gynäkologischen Onkologie

Elling, Dirk; Pink, Volker

doi:10.1007/978-3-642-76882-8

Cited by 4 publications

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“…Surveys of administrative department heads consistently indicate that appointment authority is perceived to be an important source of gubernatorial influence. [31][32][33][34][35] Findings such as these lead Beyle to argue that appointment power is "fundamental to a governor's administration, especially in relation to the state bureaucracy." [36] When looking at other gubernatorial powers, however, the picture is far more mixed.…”

Section: Literaturementioning

confidence: 99%

“…Budget powers typically have been found to be important determinants of bureaucratic influence, as have gubernatorial veto powers, although their effect appears to be much weaker than that of appointment authority. [37,38] The governor's tenure potential and reorganization powers, on the other hand, have not generally been found to be important sources of gubernatorial influence. [39][40][41] On the whole, prior research has placed a heavy emphasis on the formal powers of the governorship, although some research has suggested that informal powers deriving from the governor's popularity or prestige may also play a role.…”

Section: Literaturementioning

confidence: 99%

“…[37,38] The governor's tenure potential and reorganization powers, on the other hand, have not generally been found to be important sources of gubernatorial influence. [39][40][41] On the whole, prior research has placed a heavy emphasis on the formal powers of the governorship, although some research has suggested that informal powers deriving from the governor's popularity or prestige may also play a role. [42,43] Formal gubernatorial powers, however, have a significant drawback for students of executive-bureaucratic relations: they incorporate few Downloaded by [Hospital Miguel Servet] at 02:02 21 October 2014 direct measures of mechanisms of gubernatorial management or oversight of state bureaucratic agencies.…”

Section: Literaturementioning

confidence: 99%

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Governors and the Bureaucracy: Executive Resources as Sources of Administrative Influence

Woods

Baranowski

2007

International Journal of Public Administration

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Recent years have marked the advent of a variety of institutional mechanisms designed to enhance governors' capacity to oversee the bureaucracy. In many states, more traditional gubernatorial resources have also been bolstered. This study evaluates the effectiveness of these tools in influencing the policy activities of state agencies. We find that, in general, these resources significantly increase the amount of gubernatorial influence reported by state administrators. Our evidence suggests that institutional mechanisms specifically directed at bureaucratic influence may be taking the place of more general institutional powers as the primary mechanism for executive influence on state agencies.

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Section: Literaturementioning

confidence: 99%

Section: Literaturementioning

confidence: 99%

Section: Literaturementioning

confidence: 99%

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Governors and the Bureaucracy: Executive Resources as Sources of Administrative Influence

Woods

Baranowski

2007

International Journal of Public Administration

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“…Überden Stellenwert von Tumormarkern in der gynäkologischen Onkologie wurde in den letzten Jahren ausführlich berichtet [1][2][3][4][5][6][7][8]. Für das Ovarialkarzinom existiert mit dem tumorassoziierten Antigen CA 125 ein Marker, der sich aufgrund seiner ausreichend hohen Spezifität und Sensitivität vor allem in der Rezidiverkennung und in der Therapieerfolgskontrolle bewährt hat [1-3, 5, 6, 9, 10].…”

Section: Zusammenfassungunclassified

Sinnvoller Einsatz der Tumormarker beim Ovarialkarzinom

Meier

1997

Gynäkologe

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Das tumorassoziierte Antigen CA 125 ist aufgrund seiner hohen Spezifität von 95 % und Sensitivität von 92 % für die Rezidiverkennung beim Ovarialkarzinom ein Standardmarker. Eine Ergänzung z. B. bei muzinösen Karzinomen, bei denen das CA 125 in ca 50 % negativ ausfällt, ist der Marker 72-4. Dagegen ist das CEA wegen seiner geringen Sensitivität beim Ovarialkarzinom heute obsolet.Tumormarker sind zur Beurteilung der Effektivität einer primären, aber auch einer Rezidivtherapie von Bedeutung. Unsinnig ist jedoch eine routinemäßige Markerbestimmung bei Tumoren mit primärer Progression ohne effektive Therapiemöglichkeiten. Bei Patientinnen mit initial günstiger Prognose dagegen können Markerkontrollen sinnvoll sein. Dadurch kann eventuell nach jahrelanger Tumorfreiheit frühzeitig ein Rezidiv erkannt und die neuerliche Therapie rechtzeitig begonnen werden.Zum generellen Screening bei asymptomatischen Patientinnen können Tumormarker keinen wesentlichen Beitrag leisten, auch nicht in Kombination mit der Vaginosonographie. Eine Studie ergab, daß bei entsprechenden Verdachtskriterien, bei denen eine Abklärung durch Laparotomie oder Laparoskopie notwendig war, der positive prädiktive Wert nur 1,5 % betrug. Lediglich bei Frauen der High-risk-Gruppe mit positiver Familienanamnese und/oder BRCA1-und BRCA2-Mutationen wären Tumormarkerkontrollen zu diskutieren.

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“…The term Independence II is very difficult to apply as the material in many ways can not be distinguished from Early Dorset in other parts of Greenland (Elling 1992). The term Independence II is inherited from Knuth and is not applied outside North and Northeast Greenland.…”

mentioning

confidence: 99%

Palaeoeskimo dwellings in Greenland: A survey

Andreasen

2005

etudinuit

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In Greenland, Palaeoeskimo dwellings are mostly concentrated in the north and northeast parts of the island. Some are found in the southeast, in the west (from Nuuk to Disko Bay), and in the northwest (Inglefield Land and Washington Land). During the entire period, Palaeoeskimo dwellings show an emphasis on an axial element. In the Early Palaeoeskimo period (Saqqaq and Independence I) the fireplace is a separate square box inside two parallel rows of flags or boulders. Cooking and/or seething stones are common during Saqqaq and rare in Dorset. In Late Saqqaq, a shift in dwelling style to a platform-like dwelling is indicated by material from the Disko Bay region. During Independence II, the external borders of the axial feature often extend towards the front of the dwelling and may display "wings" at one or both ends. Late Dorset is only found in Northwest Greenland where the material from Inglefield Land documents the presence of at least four dwelling types with a clear axial element in the more substantial ruins.

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Tumormarker und Immunszintigraphie in der gynäkologischen Onkologie

Cited by 4 publications

References 0 publications

Governors and the Bureaucracy: Executive Resources as Sources of Administrative Influence

Governors and the Bureaucracy: Executive Resources as Sources of Administrative Influence

Sinnvoller Einsatz der Tumormarker beim Ovarialkarzinom

Palaeoeskimo dwellings in Greenland: A survey

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