Tumors of the Ear

Njaa, Bradley L.

doi:10.1002/9781119181200.ch21

Cited by 3 publications

(14 citation statements)

References 108 publications

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“…This finding is consistent with a recent report in which SCC was the most common malignant tumor diagnosed in the feline middle ear. 2 This is not unexpected as squamous epithelium lines the auditory canal, tympanic cavity and tympanic membranes. However, squamous epithelium also lines the ear canal and the membranous labyrinth, which explains the reported external ear canal and inner ear involvement in this study.…”

Section: Discussionmentioning

confidence: 97%

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Clinical presentation and outcome in cats with aural squamous cell carcinoma: a review of 25 cases (2010–2021)

McGrath

Chen

Abrams

et al. 2022

Journal of Feline Medicine and Surgery

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Case series summary Ear canal neoplasia is uncommon in cats. Ceruminous gland adenocarcinoma is the most frequently reported malignant neoplasm of the feline ear canal, and squamous cell carcinoma (SCC) is the most common malignant neoplasm diagnosed in the feline middle ear. However, limited information exists on the outcome of cats diagnosed with SCC of the ear canal, middle or inner ear. Therefore, the objective of this study was to describe the outcome of cats diagnosed with SCC affecting these locations. Medical records were reviewed at multiple institutions to identify cats with a definitive diagnosis of SCC. Twenty-five cats were identified. Eleven cats were treated with surgery, eight with medical management, two with coarse fractionated radiation therapy, two with a combination of coarse fractionated radiation therapy and chemotherapy, one with a combination of surgery and coarse fractionated radiation therapy, one cat with systemic chemotherapy and one cat received no treatment following diagnosis. The median survival time of cats treated with surgery was 168 days vs 85 days ( P = 0.28) for those treated palliatively with either medical management, radiation therapy, chemotherapy, or a combination of radiation therapy and chemotherapy. Relevance and novel information This case series documented that SCC of the ear canal, middle and/or internal ear is a locally aggressive tumor that carries an overall poor prognosis. The median survival time for cats treated with surgery was longer than that with any other modality, but this difference was not statistically significant.

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Section: Discussionmentioning

confidence: 97%

“…1 SCC is the most common malignant tumor diagnosed in the feline middle ear. 2 While these two tumor types are the most frequently diagnosed feline aural tumors, there are limited reports evaluating outcomes. 3,4…”

Section: Introductionmentioning

confidence: 99%

Clinical presentation and outcome in cats with aural squamous cell carcinoma: a review of 25 cases (2010–2021)

McGrath

Chen

Abrams

et al. 2022

Journal of Feline Medicine and Surgery

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“…We observed that cartilage degeneration and necrosis seem to start at the level of chondrocytes and their territorial matrix followed by degeneration of the interterritorial matrix with dissolution or decrease of glycosaminoglycans. In HE-stained sections, this is characterized by loss of basophilia, with cartilage eosinophilia, 17 whereas with safranin O stain, cartilage degeneration is apparent as progressively paler red staining. The predominant and consistent presence of cartilage degeneration, necrosis, and loss among advanced arytenoid chondritis lesions suggests that this is principally a degenerative disease rather than infectious or inflammatory.…”

Section: Discussionmentioning

confidence: 99%

Clinical and Pathological Features in Horses With Advanced Arytenoid Chondritis

et al. 2020

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Equine arytenoid chondritis causes airway obstruction and abnormal upper airway noise due to a space-occupying lesion(s) and decreased abduction. Our objective was to compare clinical scores and ultrasonographic findings with gross and microscopic lesions of naturally occurring arytenoid chondritis, in order to guide surgical treatment. Seventeen naturally affected horses with advanced/severe chronic arytenoid chondritis and 4 control arytenoid cartilages were evaluated after partial arytenoidectomy. Cartilages were sectioned caudal to the corniculate process and the body of each arytenoid was measured. We assessed total gross area (TA), percentage of viable cartilage (VC), percentage of viable cartilage on the lateral wall, and medial expansion. Retrospectively, the gross lesions were used to suggest 2 preferred surgical management (SM) groups: those requiring partial arytenoidectomy and those amendable to focal medial resection (a conservative SM). TA of horses with arytenoid chondritis was significantly larger than controls ( P = .005), due to a layered lesion composed of cavitation, granulation tissue, fibrosis, inflammation, hemorrhage, and edema, with relatively equal medial and lateral expansion that distorted the geometry of the affected cartilage. The increased TA paralleled the presence of immature cartilage with disorganized primitive mesenchymal cells. TA and SM were positively correlated ( P = .01). All cases showed varying degrees of cartilage degeneration or necrosis, more severe medially; those appearing amenable to focal medial resection arytenoid group had significantly more viable cartilage on the lateral wall ( P = .02). The gross and histopathologic findings suggest a new surgical approach—focal medial resection—that may save the lateral wall of the arytenoid.

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“…[1][2][3][4] This condition is more frequent in senior and male cats, 4 with an apparent predisposition in Abyssinian and Persian breeds. 4 The lesions are characterized grossly by multiple bluish-black cysts of varying sizes and develop in areas where modified apocrine sweat glands are present, mainly the pinna and external ear canal. 3 Lesions may be unilateral or bilateral.…”

Section: Discussionmentioning

confidence: 99%

“…3 Lesions may be unilateral or bilateral. 4 A possible etiology is uncertain, 3 and clinical signs commonly result from inflammation of the surrounding tissue and complications of external ear obstruction. 3,4 The nomenclature for describing ceruminous cystomatosis is historically inconsistent in the feline literature.…”

Section: Discussionmentioning

confidence: 99%

What is your diagnosis? External bilateral ear cysts in a cat

Paz,

Santos,

Cony

et al. 2024

Veterinary Clinical Pathol

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A 15-year-old neutered male Maine Coon cat was presented to the Department of Veterinary Pathology at the Federal University of Rio Grande do Sul for postmortem examination immediately after death related to acute pulmonary edema and suspected hypertrophic cardiomyopathy. The cat had a previous history of diabetes mellitus diagnosed 5 years ago and had been in treatment with glargine injections and dry commercial diabetic food. At the same time, small cysts were seen in the external ear canals. These cysts were not subjected to clinical intervention and had increased significantly over the last years. They were filled with dense yellow-brown secretion.Fine-needle aspirate samples were collected from the cysts, and the smears were stained with an aqueous Romanowsky stain (Panótico Rápido) for cytologic examination (Figure 1). Additional gross findings included cardiomegaly with accentuated concentric left ventricular hypertrophy and edematous lung. Tissue samples of several organs were collected for routine histopathology.

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Tumors of the Ear

Cited by 3 publications

References 108 publications

Clinical presentation and outcome in cats with aural squamous cell carcinoma: a review of 25 cases (2010–2021)

Clinical presentation and outcome in cats with aural squamous cell carcinoma: a review of 25 cases (2010–2021)

Clinical and Pathological Features in Horses With Advanced Arytenoid Chondritis

What is your diagnosis? External bilateral ear cysts in a cat

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