Tumors of the Liver and Gall Bladder

Adenoma of the gallbladder in a mongoose (Mungos mungo)

“…Histopathological findings in the current study are very similar to those previously described for gallbladder adenomas in other species, such as chimpanzee (STAROST & MARTINO, 2002) and bearded dragon (JAKAB et al, 2011). In some cases of papillary adenomas of the gallbladder, cystic projections, termed papillary cystoadenomas, can occur (CULEN & POPP, 2002); these were not observed in the current case.…”

“…Distention of the gallbladder wall in the absence of external irregularities can be detected via gross examination of the adenoma (CULEN & POPP, 2002), as in the current case. Filling of the lumen of the tubulopapillary structures of gallbladder neoplasms indicates secretion by the neoplastic epithelial cells (STAROST & MARTINO, 2002).…”

“…They have a smooth surface and are difficult to recognize if the organ is intact (CULEN & POPP, 2002 imparts a clear appearance to the cytoplasm in optic microscopy. Mitotic figures are rare, and there is no inflammatory infiltrate (CULEN & POPP, 2002). This article describes the anatomopathological findings of an adenoma of the gallbladder in a mongoose (Mungos mungo).…”

“…According to its current description, adenoma of the gallbladder is considered an incidental finding; unlike other neoplasms in this organ, there are no clinical signs indicating possible impairment of bile elimination in the small intestine (SANT 'ANA et al, 2000). Adenomas of the gallbladder are mostly observed in cattle and rarely in other domestic animals (CULEN & POPP, 2002) or wild animals (STAROST & MARTINO, 2002;JAKAB et al, 2011). Biliary tumors comprise 6% of all neoplasms in prosimian primates (REMICK et al, 2009).…”

“…Epithelial neoplasms are common (PONOMARK & MACKEY, 1976;JONES et al, 1997); whereas, mesenchymal neoplasms are extremely rare (SANT'ANA et al, 2000). Primary neoplasms of the gallbladder in domestic animals include adenomas (CULEN & POPP, 2002), leiomyomas (SANT'ANA et al, 2000), carcinomas (CULEN & POPP, 2002;SAKAI et al, 2003), and carcinoid tumors (MORREL et al, 2002). The only reports of gallbladder neoplasms in wild animals in the literature are as follows: an adenoma in a chimpanzee (STAROST & MARTINO, 2002) and a bearded dragon (JAKAB et al, 2011), an adenocarcinoma in two African lions in captivity (SAKAI et al, 2003), and biliary tumors (two adenomas and five carcinomas) in prosimian primates in a retrospective study (REMICK et al, 2009).…”