Tumors of the Nervous System

and, A. Koestner; Higgins, Robert

doi:10.1002/9780470376928.ch14

Cited by 211 publications

(449 citation statements)

References 115 publications

Supporting

Mentioning

394

Contrasting

Unclassified

Order By: Relevance

“…A unique finding in the present case was the involvement of the leptomeninges and choroid plexus. This finding is typical of metastatic lymphosarcomas involving the central nervous system in other species (Koestner and Higgins, 2002) but has not been reported in a cervid species with solitary or multicentric lymphoma. In comparison, multicentric enzootic lymphosarcoma in domestic cattle often results in infiltration of the central nervous system (Jacobs et al, 2002).…”

supporting

confidence: 52%

“…In comparison, multicentric enzootic lymphosarcoma in domestic cattle often results in infiltration of the central nervous system (Jacobs et al, 2002). In contrast to multicentric forms, primary lymphosarcomas in the central nervous system are characterized by deep-seated solitary masses, and these tumors are generally of Tcell origin (Koestner and Higgins, 2002).…”

mentioning

confidence: 99%

See 1 more Smart Citation

Multicentric T-cell Lymphosarcoma in a White-tailed Deer (Odocoileus virginianus)

Madson

Opriessnig

2009

Journal of Wildlife Diseases

View full text Add to dashboard Cite

ABSTRACT:An adult female white-tailed deer (Odocoileus virginianus) with a history of shaking, ataxia, and severe debilitation was submitted for examination. Macroscopic lesions included severe emaciation, severe abdominal and mesenteric lymphadenopathy, and several rumen-associated masses. Microscopically, the ruminal masses and lymph nodes were infiltrated by pleomorphic neoplastic lymphocytes. Similar lymphoblasts were associated with the leptomeninges, choroid plexus, and the intestinal mucosa; these cells were intensely positive for CD3 antigen, indicating their T-cell origin. Lymphoproliferative viruses (bovine leukemia virus and malignant catarrhal fever virus) or epizootic hemorrhagic disease virus were not detected by polymerase chain reaction. To our knowledge, this case represents the first report of the immunophenotype of a multicentric lymphosarcoma, metastasis involving the brain, and epitheliotropic lymphoblasts in a whitetailed deer.

show abstract

supporting

confidence: 52%

mentioning

confidence: 99%

Multicentric T-cell Lymphosarcoma in a White-tailed Deer (Odocoileus virginianus)

Madson

Opriessnig

2009

Journal of Wildlife Diseases

View full text Add to dashboard Cite

show abstract

“…A maior parte dos neoplasmas primários do SNC de cães da rotina de diagnóstico do LPV-UFSM são meningiomas (44,4%) (Fighera et al 2008). Em contraste com estudos europeus, em que os gliomas são os mais prevalentes em cães (Summers et al 1995, Koestner & Higgins 2002. Meningioma é um neoplasma do sistema nervoso central (SNC) que se origina das células meningoteliais das leptomeninges, que na maioria são considerados benignos do ponto de vista histológico, mas pelo crescimento dentro do espaço intracraniano e subdural, geram consequências malignas do ponto de vista biológico (Costa 2009).…”

Section: Introductionunclassified

“…Meningioma é um neoplasma do sistema nervoso central (SNC) que se origina das células meningoteliais das leptomeninges, que na maioria são considerados benignos do ponto de vista histológico, mas pelo crescimento dentro do espaço intracraniano e subdural, geram consequências malignas do ponto de vista biológico (Costa 2009). Nos Estados Unidos é o tumor primário do SNC mais comum em cães (40% dos tumores primários) (Snyder et al 2006, Vandevelde et al 2012) e gatos (Troxel et al 2004), e são relatados esporadicamente em cavalos (Kreeger et al 2002), bovinos (Josephson & Little 1990) e ovinos (Koestner & Higgins 2002, Vandevelde et al 2012.…”

Section: Introductionunclassified

See 1 more Smart Citation

Graduação histológica e aspectos clínico-patológicos relacionados em 22 meningiomas de cães

et al. 2018

View full text Add to dashboard Cite

Intracranial and supratentorial meningiomas were the most frequent in relation to the other intracranial or intraspinal sites. The intracranial ones were characterized mainly by clinical signs of thalamic-cortical alteration. Intraspinal ones were mainly characterized by ataxia. G-I meningiomas were the most frequent (63.6%) in dogs, followed by G-III (22.7%) and G-II (13.6%). GI were characterized by having the psammomatous subtype as the most frequent, more than one morphological pattern in the same tumor, one third presenting areas of invasion of nervous tissue, 71.4% of cases involving females, a mean age of 11 years, pure breed dogs as the most affected ones and for having the longest survival time after the manifestation of clinical signs. G-II meningiomas were characterized by having the chordoid subtype as the most frequent, invasion of nervous tissue in one third of cases, only females affected, a mean age of 12 years, two-thirds of the dogs affected were mongrels and the maximum survival time of 20 days. The G-III meningiomas were characterized by having the papillary subtype as the most frequent, invasion of the nervous tissue in 80% of the cases, 60% of the cases involving females, a mean age of 8 years, 80% of dogs affected were Boxers and the maximum survival time of 90 days. In conclusion, this study allowed to establish a relationship between the three histological grades observed in 22 cases of meningiomas in dogs with various clinical-epidemiological and pathological parameters, providing useful information for a better understanding of the correlation between the histological grading and the clinical evolution of these neoplasms.

show abstract