Tumour-to-tumour metastases: prostate carcinoma metastasising to a renal oncocytoma

Petts, Gemma; Rashid, Tina; Hrouda, David; Ngo, Nye Thane

doi:10.1136/bcr-2012-007366

Cited by 2 publications

(6 citation statements)

References 24 publications

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“…previously reported cases of donor prostatic cancer in tumor-to-tumor metastasis, none of which involved SFT. The most common recipient tumor was meningioma (7 cases) [13], followed by renal cell carcinoma (6 cases) [14][15][16], follicular adenomas of the thyroid gland (1 case) [17], renal oncocytoma (1 case) [18].This case is also the rst reported in the literature to involve prostatic cancer metastasizing to SFT.…”

Section: Discussionmentioning

confidence: 98%

Tumor-To-tumor Metastasis: Prostatic Cancer Metastasizing to Malignant Solitary Fibrous Tumor of The Lung

Lian¹,

Yang²,

Feng³

et al. 2020

Preprint

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Abstract Background: Tumor-to-tumor metastasis is an extremely rare but interesting phenomenon. Prostatic cancer metastasizing to malignant solitary fibrous tumor (SFT) of the lung has not been previously reported.Case Presentation: In this report, we describe the case of a 60-year-old man presenting a large solitary neoplasm in the left lung on computed tomography. Pathology after left lung wedge resection indicated two different cancerous cell components: SFT cells with malignant potential and prostatic cancer cells. The heterogeneous cells of prostatic origin were confirmed by using evidence from fine needle aspiration and pathology after radical prostatectomy.Conclusions: We report the first tumor-to-tumor metastasis of prostatic cancer to lung malignant SFT.

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Section: Discussionmentioning

confidence: 98%

Tumor-To-tumor Metastasis: Prostatic Cancer Metastasizing to Malignant Solitary Fibrous Tumor of The Lung

Lian¹,

Yang²,

Feng³

et al. 2020

Preprint

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“…153 Occasionally, positron emission tomography (PET)/CT scan performed for other reasons may identify renal metastasis. 42 Fluorine-18 fluorodeoxyglucose ( 18 F-FDG) PET/CT is extensively used in oncology, but its utilization in evaluating primary or metastatic involvement of the kidney is limited because physiological excretion of 18 F-FDG through the urinary tract may interfere with tumor imaging. 37 The most common CT appearance of renal metastases are bilateral, multifocal, small (< 3 cm), hypodense masses that do not commonly demonstrate hyperenhancement after contrast injection.…”

Section: Radiologic Featuresmentioning

confidence: 99%

“…In 1987, Sella and Ro 148 reported that renal cell carcinoma was the most common tumor recipient of metastasis and lung carcinoma was the most common tumor donor. A variety of renal neoplasms have been reported to be involved in tumor-to-tumor metastasis as a recipient neoplasm, [7][8][9][10][11][12][13][14][15][16][17][18][19][20] including oncocytoma, chromophobe renal cell carcinoma, and angiomyolipoma; however, clear cell renal cell carcinoma is the most common tumor recipient involved by tumor-to-tumor metastasis. The exact mechanism of tumor-to-tumor metastasis is still under investigation.…”

Section: Tumor-to-tumor Metastasismentioning

confidence: 99%

“…Metastases to the kidney can pose a significant diagnostic challenge for the pathologist as they can histologically mimic both low-grade and high-grade primary renal neoplasms. Rare cases of a secondary malignancy metastasizing to a primary renal tumor, so-called tumor-to-tumor metastasis, have also been reported 7–20. Secondary tumors of the kidney can be accurately diagnosed by correlating pathologic features with clinical and radiographic findings and the judicious use of ancillary studies 4,5…”

mentioning

confidence: 99%

“…Rare cases of a secondary malignancy metastasizing to a primary renal tumor, so-called tumor-totumor metastasis, have also been reported. [7][8][9][10][11][12][13][14][15][16][17][18][19][20] Secondary tumors of the kidney can be accurately diagnosed by correlating pathologic features with clinical and radiographic findings and the judicious use of ancillary studies. 4,5…”

mentioning

confidence: 99%

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Secondary Tumors of the Kidney: A Comprehensive Clinicopathologic Analysis

Saeed

Osunkoya²

2022

Advances in Anatomic Pathology

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Metastases to the kidney are rare and were historically described in autopsy series, and the incidence ranged between 2.36% and 12.6%. However, in the contemporary literature with the improvements in imaging modalities (computed tomography scan and magnetic resonance imaging) and other health care screening services, metastatic tumors to the kidney are being diagnosed more frequently in surgical specimens. The utility of needle core biopsies in the primary evaluation of renal masses has also increased the number of sampled metastases, and as a result, only limited histologic material is available for evaluation in some cases and may potentially lead to diagnostic pitfalls. In the last decade, a few large clinical series have been published. In these series, the majority of metastatic tumors to the kidney are carcinomas, with the lung being the most common primary site. A significant number of the various tumor types with metastasis to the kidney are also associated with widespread metastases to other organs, and the renal metastasis may present several years after diagnosis of the primary tumor. The majority of secondary tumors of the kidney are asymptomatic, incidentally discovered, and solitary. There should be a high index of suspicion of metastasis to the kidney in patients with an associated enlarging renal lesion with minimal to no enhancement on imaging and tumor progression of a known high-grade nonrenal malignancy. Secondary tumors of the kidney can be accurately diagnosed by correlating histopathologic features with clinical and radiographic findings and the judicious use of ancillary studies.

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Tumour-to-tumour metastases: prostate carcinoma metastasising to a renal oncocytoma

Abstract: SUMMARYThis is a case report of prostate carcinoma metastasising to a renal oncocytoma. The report demonstrates the unusual presentation of metastases from a common cancer to a common benign tumour, and reviews the rare phenomenon of tumour-to-tumour metastases. BACKGROUND

Cited by 2 publications

References 24 publications

Tumor-To-tumor Metastasis: Prostatic Cancer Metastasizing to Malignant Solitary Fibrous Tumor of The Lung

Tumor-To-tumor Metastasis: Prostatic Cancer Metastasizing to Malignant Solitary Fibrous Tumor of The Lung

Secondary Tumors of the Kidney: A Comprehensive Clinicopathologic Analysis

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