Tumours of the head and neck in the elderly: analysis of 190 patients

Rapidis, Alexander D.; Keramidas, Triantafyllos; Panagiotopoulos, Helen; Andressakis, D; Angelopoulos, A.

doi:10.1016/s1010-5182(98)80005-x

Cited by 14 publications

(7 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Studies from other parts in the African continent have shown that pleomorphic adenoma account for 40-63% of all parotid gland tumours (3,(25)(26)(27)(30)(31)(32). Our results differ with several other studies that reported that about 90% of the tumours were located in the major salivary glands (6,33,34).…”

Section: Discussioncontrasting

confidence: 99%

“…They constitute a substantial proportion of all tumours of the oro-facial region (2)(3)(4)(5). Head and neck tumours represent approximately 5% of human neoplasms, and out of these, salivary gland neoplasms constitute 10% (4,6). The 1972 World Health Organisation (WHO) classification of salivary gland tumours was revised in 1992 and recategorised several of the salivary gland tumours (7,8).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Salivary gland tumours in Tanzania

Masanja¹,

Kalyanyama²,

Simon³

2004

E Af Med Jrnl

View full text Add to dashboard Cite

Objective: To determine the pattern of occurrence of salivary gland tumours in Tanzania over a period of twenty years. Design: Cross-sectional retrospective study. Setting: Two referral centres; Muhimbili National Hospital (MNH) and Kilimanjaro Christian Medical Centre (KCMC). Methods: Medical records of patients who presented with tumours of the salivary glands in the two major referral centres over a period of twenty years from 1982 to 2001 were reviewed. Data regarding demographic, clinical and histologic information was analysed. Results: Salivary gland tumours constituted 6.3% of all oral-facial tumours and tumour like lesions. Among the salivary gland tumours, 54% were benign and 46% malignant, which occurred in 80 males and 53 females. Peak age was between 20 and 49 years, with a malefemale ratio of 1.5:1 (p< 0.05). Pleomorphic adenoma was the commonest occurring tumour (44.4%) followed by adenoid cystic carcinoma (24.8%), mucoepidermoid carcinoma (9.8%) and adenocarcinoma (6.5%). Among the benign tumours, pleomorphic adenoma dominated (83.9%), followed by adenoma (9.9%). Among malignant tumours adenoid cystic carcinoma occurred in 54.3% followed by mucoepidemoid carcinoma (22.9%) and adenocarcinoma (11.4%). The parotid gland was the commonest site of occurrence followed by the palate. At initial stages the only complaint from the patients was essentially a slowly growing painless swelling. Treatment modality was mainly surgical in both benign and malignant tumours, however, for malignant tumours radiotherapy alone or in combination with surgery was sometimes employed. Conclusion: On average salivary gland tumours occurred at a relatively younger age compared to that reported in Western countries. Contrary to reports from Europe and America, adenoid cystic carcinoma was the most frequently occurring malignant salivary gland tumour. Late presentation was seen as a problem that needs to be addressed in order to maximise the effectiveness of treatment.

show abstract

Section: Discussioncontrasting

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Salivary gland tumours in Tanzania

Masanja¹,

Kalyanyama²,

Simon³

2004

E Af Med Jrnl

View full text Add to dashboard Cite

show abstract

“…We have taken 70 years as a cut‐off point. This age limit is frequently used, 1–3,8,10,22 although some authors have selected an older 9,11,23 or younger age limit 12,24 …”

Section: Discussionmentioning

confidence: 99%

“…However, doctors and patients, or their family also, may have several non‐medical reasons for non‐standard treatment. Retrospective studies demonstrate that radical surgical treatment can be performed safely in elderly patients if no severe co‐morbid conditions exist 1,3,5,8–14 …”

mentioning

confidence: 99%

Elderly patients with head and neck cancer: short-term effects of surgical treatment on quality of life

Derks¹,

Leeuw

Hordijk³

et al. 2003

Clin Otolaryngol

View full text Add to dashboard Cite

Elderly patients with head and neck cancer are less likely to be treated surgically. However, little is known about surgical outcome and quality of life (QOL) in elderly patients after a major surgery. This prospective study compared the QOL and the surgical outcome of 54 elderly (> or =70 years) and 75 younger patients (45-60 years) with carcinoma of the oral cavity (stage > or = II), pharynx (stage > or = II) or larynx (stage > or = III). Before and 3 months after surgery, the patients completed questionnaires about QOL (EORTC QLQ-C30 and QLQ-H&N35) and depression (CES-D). Before treatment, elderly and younger patients did not differ in QOL. Three months after the treatment, both groups scored worse on most QOL aspects, but there were no significant differences between the elderly and the younger patients. Surgical and systemic complication rates were similar for both the groups. In conclusion, we found no significant differences in the complication rate and QOL aspects between surgically treated elderly and younger patients.

show abstract

“…These basic pathological differences will inherently affect outcome (Franceschi et al 2000). For most types of solid epithelial tumors, old age itself does not appear to function as an independently negative prognostic variable for cancer-specific survival; a finding evident in recent studies assessing colorectal cancer (Audisio, Cazzaniga, et al 1997; Staudacher et al 2000; Chiappa et al 2001), gastric cancer (Lo et al 1996; Kitamura et al 1999), esophageal carcinoma (Jougon et al 1997; Poon et al 1998), liver (Chiappa et al 1999), head & neck (Robinson 1994; Rapidis et al 1998) and breast cancers (Veronesi et al 1988; Desch et al 1993; Newschaffer et al 1996; Siliman 1996). …”

Section: Tumor Biologymentioning

confidence: 99%

Risk assessment for cancer surgery in elderly patients

Ramesh¹,

Boase²,

Audisio³

2006

Clinical Interventions in Aging

View full text Add to dashboard Cite

Global growth of the elderly population is requiring healthcare providers to cater for an expanding elderly cancer subpopulation. The aggression with which cancer should be treated in this subpopulation is an ethical dilemma and is an ongoing debate, as surgeons have feared increases in postoperative morbidity and mortality. As a result elderly patients often receive suboptimal cancer treatment. The need for standardization of cancer surgery is well recognized despite the difficulties in view of heterogeneity of the group. In this article, epidemiological changes, tumor biology specific to elderly cancer are visited, operative risk assessment tools are discussed, and interim results of ongoing multinational investigation ie, PACE (Preoperative Assessment of Cancer Elderly) revealed.

show abstract

Tumours of the head and neck in the elderly: analysis of 190 patients

Cited by 14 publications

References 25 publications

Salivary gland tumours in Tanzania

Salivary gland tumours in Tanzania

Elderly patients with head and neck cancer: short-term effects of surgical treatment on quality of life

Risk assessment for cancer surgery in elderly patients

Contact Info

Product

Resources

About