Foams are commonly used as sound absorbers and thermal insulators for many industrial and construction applications. The insulating materials market is currently dominated by inorganic fibres like glass and mineral wool, as well as plastic foams. However, worldwide plastics consumption produces huge amounts of waste, generating concerns about soil, air and especially seawater pollution. Hence, new methods for recycling marine microplastic litter according to cleaner production criteria are being sought. This paper presents a novel, sustainable and eco-friendly foamy material made of microplastic waste, namely polyethylene terephthalate (PET) and polystyrene (PS), incorporated into a bio-based matrix. Samples with different compositions were prepared and then characterized for sound absorption properties. Evidence is presented of very good acoustic performances and of how the acoustic characteristics of the end product can be customized using different microplastic content and type. This allows envisioning many industrial and civil applications for this novel open-cell material.