A differential absorption lidar system for detection of atmospheric pollutants based on the middle infrared tandem optical parametric oscillator is presented. The characteristics of the signal obtained by detecting radiation backscattered from different topographical objects were measured in the field test of the system. These characteristics were used to calculate the minimum detectable concentration of several atmospheric pollutants: ozone, methane, ammonia, etc. Most of the gases can be detected below typical background concentrations for the low-polluted atmosphere.