Given the sub-wavelength trapping challenges in the optical tweezers, the plasmonic tweezers serve as a bridge by breaking the diffraction limit. Hence, the development of plasmonic tweezers can open up many potential applications in biology, medicine, and chemistry. In this paper, using localized surface plasmons (LSPs) of graphene nanodisk with a resonance frequency of 20 THz, we design a lab-on-a-chip optophoresis system, which can be utilized to effectively trap the nanoparticles. The LSPs of graphene nanodisk generate a large field gradient in the deep sub-wavelength area around the resonance frequency. We show that by an appropriate choice of chemical potentials of the graphene nanodisks, the strong optical near-field forces desired for trapping can be generated under the illumination of the THz source when the polystyrene (PS) nanoparticles are located in the vicinity of graphene nanodisks. Numerical simulations show that the designed system with graphene nanodisks of 250 nm in diameter and chemical potentials of µ c = 0.6 eV can trap the PS nanoparticles of 12 nm in diameter and larger with a THz source intensity of 19 mW/µm 2 , demonstrating acceptable sensitivities for variations in the nanoparticle diameter and refractive index. Moreover, at the same source intensity, the graphene nanodisks with µ c = 0.7 eV can trap the PS nanoparticle as small as 9.5 nm in diameter.