Tuning of rheological behavior of soybean lipophilic protein-stabilized emulsions

Sirison, Jiraporn; Ishii, Toya; Matsumiya, Kentaro; Higashino, Yuki; Nambu, Yuko; Sakai, Masahiko; Sugiyama, Masahiro; Matsumura, Yukihiko

doi:10.1016/j.foodhyd.2023.108745

Cited by 5 publications

(2 citation statements)

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“…In pharmaceutical formulations, the natural emulsifiers found in SO, particularly lecithin, take center stage as versatile and invaluable components. Lecithin, extracted from SO, possesses remarkable emulsifying properties that make it a stabilizing force in various liquid formulations, including emulsions and suspensions [84]. This natural emulsifier plays a crucial role in enhancing the stability and dispersion of active pharmaceutical ingredients (APIs), ensuring uniform distribution, and facilitating the administration of medications.…”

Section: Emulsifying Agentsmentioning

confidence: 99%

Soybean Oil: A Versatile Asset in Pharmaceutical Drug Delivery

Mohanty,

Behera,

Kumar Shaw

et al. 2024

Agricultural Sciences

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Soybean oil (SO), a lucrative and widely utilized vegetable oil, is used not only in the pharmaceutical industry but also to produce green diesel and several biomedical applications. SO is rich in healthy fats, including linoleic acid (54%), oleic acid (23%), palmitic acid (11%), linolenic acids (8%), and stearic acid (4%). Its high unsaturated fatty acid content makes it ideal for medicinal purposes. In topical application, SO provides anti-inflammatory and soothing benefits. The presence of SO in lipid-based medication improves the therapeutic efficacy and bioavailability of poorly water-soluble drugs. Its emulsifying properties support the development of Self-Emulsifying Drug Delivery Systems (SEDDS) and Self-Micro Emulsifying Drug Delivery Systems (SMEDDS), helping the oral administration of hydrophobic drugs. Additionally, soybean oil is included in total parenteral nutrition (TPN) solutions to provide essential fatty acids to patients unable to swallow. SO, biocompatibility, stability, and low toxicity make it a brilliant base for transcutaneous and topical delivery systems, enlightening the absorption of active medicinal ingredients. In gist, unique properties and a wide variety of applications make SO a star material in pharmaceuticals to enhance solubility, bioavailability, and the development of safe and effective drugs.

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Section: Emulsifying Agentsmentioning

confidence: 99%

Soybean Oil: A Versatile Asset in Pharmaceutical Drug Delivery

Mohanty,

Behera,

Kumar Shaw

et al. 2024

Agricultural Sciences

View full text Add to dashboard Cite

show abstract

“…mouthfeel in foods). 4 In addition to more conventional O/W emulsions, where dispersed oil droplets are stabilized by a molecularly adsorbed protective layer, a number of more novel designs for delivery of the required active substances include microemulsions, multiple emulsions, multilayer stabilized emulsions, high internal phase emulsions (i.e. HIPE), Pickering emulsions and emulsion gels.…”

Section: Introductionmentioning

confidence: 99%