Tuning the self-assembly of a ditopic crown ether functionalized oligo(p-phenylenevinylene)

Janssen, Pim G. A.; Jonkheijm, Pascal; Thordarson, Pall; Gielen, Jeroen C.; Christianen, P.C.M.; Dongen, Joost L. J. van; Meijer, E. W.; Schenning, Albertus P. H. J.

doi:10.1039/b702298k

Cited by 19 publications

(17 citation statements)

References 45 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Equation (22) is very similar to (18) and the two unknown variables, K a and Y HG , can be obtained in a similar manner by titration and fitting the results data to (22) using a nonlinear regression program.…”

Section: The 1 : 1 Equilibriamentioning

confidence: 99%

“…Equations (9) and (17) can now be combined to give (18), which describes the experimentally observed change in a physical property ( Y ) as a function of two known ([H] 0 and [G] 0 ) variables and two unknowns (K a and Y HG ).…”

Section: The 1 : 1 Equilibriamentioning

confidence: 99%

Section: The 1 : 1 Equilibriamentioning

confidence: 99%

“…Using a variety of software packages or programs, it is then possible to fit the resulting binding isotherm to (18) by nonlinear regression methods to obtain the best estimates for K a and Y HG , as discussed further below. Equation (18) can be modified for any method where the physical property of interest is depended on concentration. In some situation, for example, NMR, the physical property is not concentration, but rather mole fraction, dependent with the mole fraction f x depends on the total concentration of species X = [X] 0 according to (19).…”

Section: The 1 : 1 Equilibriamentioning

confidence: 99%

See 3 more Smart Citations

Binding Constants and Their Measurement

Thordarson

2012

Supramolecular Chemistry

Self Cite

View full text Add to dashboard Cite

This chapter is concerned with how binding constants in supramolecular chemistry are determined. It is divided into three main sections. The first and largest section of this chapter details the key mathematical equations used to describe supramolecular equilibria, including common ones such as 1:1, 1:2, and dimerization as well as less frequently encountered 2:1, 2:2, and linear aggregation models. Details are also provided on how these equations are used with commonly used experimental techniques such as NMR, UV–vis, and fluorescence spectroscopy as well as calorimetry. The next section then discusses methods used for the determination of stoichiometry, including Job's method. The final section is concerned with data analysis, including model selection and comparison, global analysis, estimation of uncertainties, software consideration, and a brief review of selected software packages available for analyzing data from supramolecular titrations. Representative examples from the literature are also included to highlight the topics covered in this chapter.

show abstract

Section: The 1 : 1 Equilibriamentioning

confidence: 99%

Section: The 1 : 1 Equilibriamentioning

confidence: 99%

Section: The 1 : 1 Equilibriamentioning

confidence: 99%

Section: The 1 : 1 Equilibriamentioning

confidence: 99%

See 2 more Smart Citations

Binding Constants and Their Measurement

Thordarson

2012

Supramolecular Chemistry

Self Cite

View full text Add to dashboard Cite

show abstract

“…[31][32][33][34][35][36][37][38] Furthermore, this technique has recently been used to characterize a variety of supramolecular complexes. [39][40][41][42][43][44][45] Qualitative information on the binding strength of the supramolecular complexes can be obtained by collision-induced-dissociation (CID) experiments. [46] Recently, we have reported the ssDNA-templated self-assembly of naphthalene and oligo(p-phenylene)vinylene di-A C H T U N G T R E N N U N G aminotriazine derivatives (G1 and G4, respectively) that bind to a complementary strand of oligothymine (dT40, in which 40 is the number of thymines) to yield uniform objects ( Figure 1 and Scheme 1).…”

Section: Introductionmentioning

confidence: 99%

Electrospray‐Ionization Mass Spectrometry for Screening the Specificity and Stability of Single‐Stranded‐DNA Templated Self‐Assemblies

Janssen

Dongen

Meijer

et al. 2008

Chemistry A European J

View full text Add to dashboard Cite

Supramolecular complexes consisting of a single-stranded oligothymine (dTn) as the host template and an array of guest molecules equipped with a complementary diaminotriazine hydrogen-bonding unit have been studied with electrospray-ionization mass spectrometry (ESI-MS). In this hybrid construct, a supramolecular stack of guest molecules is hydrogen bonded to dTn. By changing the hydrogen-bonding motif of the DNA host template or the guest molecules, selective hydrogen bonding was proven. We were able to detect single-stranded-DNA (ssDNA)-guest complexes for strands with lengths of up to 20 bases, in which the highest complex mass detected was 15 kDa; these complexes constitute 20-component self-assembled objects. Gas-phase breakdown experiments on single- and multiple-guest-DNA assemblies gave qualitative information on the fragmentation pathways and the relative complex stabilities. We found that the guest molecules are removed from the template one by one in a highly controlled way. The stabilities of the complexes depend mainly on the molecular weight of the guest molecules, a fact suggesting that the complexes collapse in the gas phase. By mixing two different guests with the ssDNA template, a multicomponent dynamic library can be created. Our results demonstrate that ESI-MS is a powerful tool to analyze supramolecular ssDNA complexes in great detail.

show abstract

Fluorescent Nanoparticles Based on Self‐Assembled π‐Conjugated Systems

2010

Self Cite

View full text Add to dashboard Cite

pi-Conjugated molecules are interesting components to prepare fluorescent nanoparticles. From the use of polymer chains that form small aggregates in water to the self-assembly of small chromophoric segments into highly ordered structures, the preparation of these materials allows to develop systems with applications as sensors or biolabels. The potential functionalization of the nanoparticles can lead to specific probing. This progress report describes the recent advances in the preparation of such emittive organic nanoparticles.

show abstract

Tuning the self-assembly of a ditopic crown ether functionalized oligo(p-phenylenevinylene)

Cited by 19 publications

References 45 publications

Binding Constants and Their Measurement

Binding Constants and Their Measurement

Electrospray‐Ionization Mass Spectrometry for Screening the Specificity and Stability of Single‐Stranded‐DNA Templated Self‐Assemblies

Fluorescent Nanoparticles Based on Self‐Assembled π‐Conjugated Systems

Contact Info

Product

Resources

About