Tunnelling the structural insights between poly(N-isopropylacrylamide) and imidazolium sulfate ionic liquids

Manipulation of Thermoresponsive Polymers Using Biomolecules

“…Novel thermoresponsive materials are being developed rapidly in parallel with our ability to synthesize structurally complex macromolecules or biomacromolecules. Furthermore, future advances in polymer chemistry will undoubtedly result in the development of even smarter materials with tunable and predictable properties. ,− Knowledge of the types of stimuli that can induce desired responses in polymeric systems and the effects of functionalities are essential for assessing the potential of responsive materials. A wide range of functionalities and interesting properties arise from the conformations of macromolecule/biomacromolecule complexes or the influence of solvents on transitions, which allow phase transitions at the molecular level to be realized as dramatic changes in material properties in the nanoscale range. − …”

“…Polymer response to different stimuli remains a hot research topic for those designing polymers that mimic biological molecules . Researchers have already prepared polymers that respond to light, pH, temperature, magnetic and electric fields, ultrasound, osmolytes, ionic liquids, chemical agents, and solvents. − Phase separation is the most common polymer response to external stimuli and occurs due to modulations of interactions between polymeric chains and solvents without changing the chemical configuration of the polymer. − Natural processes play an essential role in bridging the gap between the biological realm and artificial systems. Responses to external stimuli are well demonstrated in nature by the foliage folding of plants in response to touch, the color changes of chameleons, the movements of sunflowers, venus flytraps, and the opening of morning glory in sunlight. ,, These responses have encouraged studies on polymer responses to biochemical agents, proteins, enzymes, glucose, and antigens, and results to date indicate these approaches have huge in vivo applications. − …”

The Method of Direct and Reverse Phase Portraits as a Tool for Systematizing the Results of Studies of Phase Transitions in Solutions of Thermosensitive Polymers

“…Venkatesu et al studied the interaction of PVCL, their interactions with additives such as 1-allyl-3-methylimidazolium bromide, multi-walled carbon nanotubes, methylamine-based osmolytes, PNIPAM, deep eutectic solvents, and tryptophan-based amino acid ionic liquids, and their potential biomedical applications, laying the groundwork for innovative advances in drug delivery and biotechnology [ 105 , 106 , 107 , 108 , 109 , 110 , 111 , 112 , 113 , 114 ].…”