Turbinoplasty with Quantic Molecular Resonance in the Treatment of Persistent Moderate-Severe Allergic Rhinitis: Comparative Analysis of Efficacy

Businco, L; Businco, Andrea Di Rienzo; Ventura, Laura; Laurino, Salvatore; Lauriello, M

doi:10.2500/ajra.2014.28.3990

Cited by 16 publications

(8 citation statements)

References 11 publications

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“…21 The underlying rationale is usually to avoid aggressive reductions in tissue volume to prevent empty nose syndrome. 2,22,23 In the present study, no differences were detected in the frequency of NOAS at 90 days regardless of the type of technique employed for turbinate reduction.…”

Section: Discussioncontrasting

confidence: 60%

Inferior Turbinate Reduction during Rhinoplasty: Is There Any Effect on Rhinitis Symptoms?

Garcia

Moura

Rodrigues

et al. 2021

Int Arch Otorhinolaryngol

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Introduction Inferior turbinate surgery is often performed concomitantly with rhinoseptoplasty. As inferior turbinates play a major role in allergic rhinitis, it seems reasonable to suggest that inferior turbinate surgery reduces allergy. Objective To assess the impact of nasal turbinate surgery on non-obstructive allergic symptoms (nasal discharge, sneezing, pruritus, and allergic conjunctivitis) and on the use of allergic medication in patients with allergic rhinitis undergoing rhinoseptoplasty. Methods Secondary analysis of aggregated data from two randomized controlled trials. Participants with allergic rhinitis aged ≥ 16 years were recruited. Data from two groups were analyzed: patients with rhinoseptoplasty and concomitant turbinate reduction (intervention group) and patients with rhinoseptoplasty only (control group). The 90-day postoperative frequency of non-obstructive allergic symptoms and of nasal steroid and oral antihistamine use were analyzed. Results A total of 100 patients were studied. The groups were similar in terms of allergic symptom intensity and mean age. The frequency of non-obstructive allergic symptoms decreased 90 days postoperative in both groups (p < 0.01). There was no difference between the groups in the frequency of non-obstructive allergic symptoms at 90 days (p = 0.835). Topical nasal steroid and oral histamine antagonist use decreased in the intervention group at 90 days (p < 0.05). Conclusions Ninety days after the surgery, turbinate reduction performed in association with rhinoseptoplasty did not reduce the frequency of non-obstructive allergic symptoms more than rhinoplasty alone. However, the observed decrease in nasal steroid and oral antihistamine use suggests an impact of turbinate reduction on medication use in patients with allergic rhinitis undergoing rhinoseptoplasty. Trial Registration ClinicalTrials.gov database (NCT01457638 and NCT02231216).

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Section: Discussioncontrasting

confidence: 60%

Inferior Turbinate Reduction during Rhinoplasty: Is There Any Effect on Rhinitis Symptoms?

Garcia

Moura

Rodrigues

et al. 2021

Int Arch Otorhinolaryngol

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“…This means that more severe AR or a greater degree of nasal obstruction is more likely to cause ETD. Many patients with severe AR are prone to concomitant inferior turbinate hypertrophy [ 24 ] and torus tubarius swelling, causing both nasal obstruction and ETD [ 25 ]. Previous studies have shown that patients with nasal obstruction due to inferior turbinate enlargement or nasal septum deviation have significantly higher ETDQ-7 scores than healthy controls [ 26 ].…”

Section: Discussionmentioning

confidence: 99%

Eustachian tube dysfunction in patients with house dust mite-allergic rhinitis

Liang

Tian

et al. 2020

Clin Transl Allergy

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Background One of the important pathogeneses of eustachian tube dysfunction (ETD) is nasal inflammatory disease. The prevalence of allergic rhinitis (AR) in adults ranges from 10 to 30% worldwide. However, research on the status of eustachian tubes in AR patients is still very limited. Methods This prospective controlled cross-sectional study recruited 59 volunteers and 59 patients with AR from Sun Yat-sen Memorial Hospital. Visual analogue scale (VAS) scores for AR symptoms and seven-item Eustachian Tube Dysfunction Questionnaire (ETDQ-7) scores were collected for both groups. Nasal endoscopy, tympanography and eustachian tube pressure measurement (tubomanometry, TMM) were used for objective assessment. All AR patients underwent 1 month of treatment with mometasone furoate nasal spray and oral loratadine. Then, the nasal condition and eustachian tube status were again evaluated. Results TMM examination revealed that 22 patients (39 ears, 33.1%) among the AR patients and 5 healthy controls (7 ears, 5.9%) had abnormal eustachian pressure. Twenty-two AR patients (37.3%) and 9 healthy controls had an ETDQ-7 score ≥ 15. With regard to nasal symptoms of AR, the VAS scores of nasal obstruction were correlated with the ETDQ-7 scores, and the correlation coefficient was r = 0.5124 ( p < 0.0001). Nasal endoscopic scores were also positively correlated with ETDQ-7 scores, with a correlation coefficient of 0.7328 ( p < 0.0001). After 1 month of treatment, VAS scores of nasal symptoms, endoscopic scores and ETDQ-7 scores were significantly decreased in AR patients ( p < 0.0001), and TMM examination also suggested that eustachian tube function was significantly improved after treatment ( p < 0.0001). Conclusions AR patients, especially those with severe nasal obstruction, could have ETD. The local conditions of the pharyngeal orifices of the eustachian tubes are closely related to the symptoms of ETD. After treatment with nasal glucocorticoids and oral antihistamines, eustachian tube function can significantly improve as nasal symptoms subside. Trial registration Chinese Clinical Trial Registery (ChiCTR2000029071) Registered 12 January 2020—Retrospectively registered, http://www.chictr.org.cn/edit.aspx?pid=48328&htm=4

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“…20 Several studies showed that QMR treatment can be considered a safe and minimally invasive surgical procedure with the lowest mucosal damage, minor discomfort, and a low risk of side effects because it uses lower temperatures minimizing adverse effects. 21 The QMR is based on the fundamental principles of quantum theory: Any form of energy is transmitted from a source to a body in tiny discrete packets of energy that Max Planck called ''energy elements'' or Quanta. The mechanism of action is based on molecular bounds breaking: QMR generates frequencies that makes bounds resonate and break keeping the surrounding tissues at a low temperature (<45 C).…”

Section: Discussionmentioning

confidence: 99%

The Role of Quantic Molecular Resonance (QMR) in the Treatment of Inferior Turbinate Hypertrophy (ITH): Our Experience With Long-Term Follow-Up in Allergic and Nonallergic Rhinitis Refractory to Medical Therapy. Preliminary Results

et al. 2021

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Objective: The aim of this study was to assess the long-term effectiveness of quantic molecular resonance (QMR) in the treatment of inferior turbinate hypertrophy (ITH) in allergic and nonallergic rhinitis refractory to medical therapy. Methods: This study enrolled 281 patients, 160 males (56.9%) and 121 females (43.1%), mean age 37.8 ± 4.1 years, range 18 to 71. Fifty-four patients have been lost to follow up and have been therefore excluded from the final analysis. Based on skin prick test results, 69 patients were considered allergic (group A) and 158 nonallergic (group B). All subjects underwent before surgery (T0) and 3 (T1), 12 (T2), 24 (T3), and 36 months (T4) after QMR treatment to: 4-phase rhinomanometric examination, nasal endoscopy evaluation, and visual analogue scale to quantify the subjective feelings about nasal obstruction. Results: Subjective and objective parameters showed statistically significant improvement in both groups. Group B parameters not changed during follow-up, while group A showed significant worsening between T1 and subsequent assessments. T4 outcome indicates a better result in nonallergic patients. Conclusions: In accordance with the literature, our preliminary data validate QMR treatment as a successful therapeutic option for nasal obstruction due to ITH. Nonallergic patients had a very good T4 outcome. Allergic patients showed a worsening trend after 1 year probably due to other causes.

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Turbinoplasty with Quantic Molecular Resonance in the Treatment of Persistent Moderate-Severe Allergic Rhinitis: Comparative Analysis of Efficacy

Cited by 16 publications

References 11 publications

Inferior Turbinate Reduction during Rhinoplasty: Is There Any Effect on Rhinitis Symptoms?

Inferior Turbinate Reduction during Rhinoplasty: Is There Any Effect on Rhinitis Symptoms?

Eustachian tube dysfunction in patients with house dust mite-allergic rhinitis

The Role of Quantic Molecular Resonance (QMR) in the Treatment of Inferior Turbinate Hypertrophy (ITH): Our Experience With Long-Term Follow-Up in Allergic and Nonallergic Rhinitis Refractory to Medical Therapy. Preliminary Results

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