Turbo-PUVA: Dihydroxyacetone-Enhanced Photochemotherapy for Psoriasis

Taylor, Charles R.; Kwangsukstith, Chartchai; Wimberly, Joanne; Kollias, Nikiforos; Anderson, R. Rox

doi:10.1001/archderm.135.5.540

Cited by 31 publications

(22 citation statements)

References 13 publications

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“…23 Dihydroxyacetone, an isomer of glyceraldehyde, is present in most ''sunless'' tanning products, forming a brown pigment that simulates a suntan by the Maillard polymerization reaction. 28 The toxicity of any drug depends on its dose. Our study showed mild reversible side effects of the glyceraldehyde treatment in the peripheral cornea and the extraocular muscles, whereas the retina was unaffected.…”

Section: Discussionmentioning

confidence: 99%

Crosslinking of scleral collagen in the rabbit using glyceraldehyde

Wollensak¹,

Iomdina²

2008

Journal of Cataract and Refractive Surgery

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Section: Discussionmentioning

confidence: 99%

Crosslinking of scleral collagen in the rabbit using glyceraldehyde

Wollensak¹,

Iomdina²

2008

Journal of Cataract and Refractive Surgery

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“…There are no specific guidelines on the use of phototherapy while on DHA camouflage. Interestingly though, in a study by Taylor et al, [30] in 30 psoriatic patients on PUVA treatment, it was suggested that protection of uninvolved skin by DHA during PUVA treatment allows higher UV-A exposures to be tolerated, demonstrates faster clearing and requires fewer treatments to clear psoriasis. This could probably be extrapolated to the use of PUVA in vitiligo too.…”

Section: Kaliyadan and Kumarmentioning

confidence: 99%

Camouflage for patients with vitiligo

Kaliyadan¹,

Kumar²

2012

Indian J Dermatol Venereol Leprol

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Vitiligo is known to be associated with social stigma and a decreased quality of life, especially when lesions are located over the face. While there are numerous treatment options for vitiligo, most of these need a long time to produce good cosmetic results. Camouflaging the skin lesions can be a useful option in such patients. The proper use of camouflage has been shown to improve the quality of life in patients with vitiligo. In this article, we discuss the different camouflage options available in vitiligo - products and techniques with their relative advantages and disadvantages.

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“…It appears to be useful for the treatment of age-related macular generation and choroidal melanoma (42). BPD-PDT also has been tested for treatment of atherosclerotic plaques (43) and psoriasis (44,45 (48), and mono-L-aspartyl chlorin e6 (NPe6; l abs @ 664 nm) has recently entered clinical trials for superficial malignancies of the skin and nasopharynx (49).…”

Section: Photosensitizers and Clinical Trialsmentioning

confidence: 99%

[No Title Available]

Sibata

Colussi

Oleinick

et al. 2000

Braz J Med Biol Res

156

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A new concept in the therapy of both neoplastic and non-neoplastic diseases is discussed in this article. Photodynamic therapy (PDT) involves light activation, in the presence of molecular oxygen, of certain dyes that are taken up by the target tissue. These dyes are termed photosensitizers. The mechanism of interaction of the photosensitizers and light is discussed, along with the effects produced in the target tissue. The present status of clinical PDT is discussed along with the newer photosensitizers being used and their clinical roles. Despite the promising results from earlier clinical trials of PDT, considerable additional work is needed to bring this new modality of treatment into modern clinical practice. Improvements in the area of light source delivery, light dosimetry and the computation of models of treatment are necessary to standardize treatments and ensure proper treatment delivery. Finally, quality assurance issues in the treatment process should be introduced.

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Turbo-PUVA: Dihydroxyacetone-Enhanced Photochemotherapy for Psoriasis

Cited by 31 publications

References 13 publications

Crosslinking of scleral collagen in the rabbit using glyceraldehyde

Crosslinking of scleral collagen in the rabbit using glyceraldehyde

Camouflage for patients with vitiligo

[No Title Available]

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