Ignition and relighting in supersonic flows is an important challenge for the design of hypersonic propulsion systems. Supersonic compressible flows of interest exhibit much larger local variations in velocity, shear, and thermodynamic state than their incompressible counterparts. Thus, it is of interest to study the relationship between ignition kernel evolution, the initial spark location, and the kernel's subsequent flow state history. We leverage the flexibility of a laser plasma ignition system to systematically explore a large set of spark locations on the symmetry plane of an ethylene jet in supersonic crossflow setup. CH* measurements are used to visualize chemically active regions and results are correlated with flow field properties derived from Mie-scattering data of the non-reacting flow field. Our study describes the laser plasma properties in detail and scrutinizes the effect of turbulent mixing and flow dilatation on ignition kernels. Finally, the results yield general guidelines for favorable ignition locations in the engineering design of chemically reactive compressible flows.