Turcot syndrome and Gardner's syndrome in a female patient with familial colon adenomatosis. A case report and literature review

Eponyms in digestive system pathology

“…Gardner syndrome. [19][20][21] Gardner syndrome, Turcot syndrome, or gastric adenocarcinoma and proximal polyposis of the stomach are believed to be a spectrum of familial adenomatous polyposis (FAP), depending on the specific mutation within the adenomatous polyposis coli gene (APC). FAP is a rare genetic disorder with autosomal dominant inheritance, defined by numerous adenomatous polyps, which inevitably progress to colorectal carcinoma unless detected and managed early.…”

“…He first described this finding in the 1860s; he later found the same sign in himself, was subsequently diagnosed with gastric cancer and died soon thereafter Turcot syndrome. 20,21 It is a rare hereditary syndrome characterized by a combination of brain tumors and colorectal cancer. It was first reported by Canadian surgeon Jacques Turcot .…”