Türk Soluk Ciğerotu (Chiloscyphus polyanthos (L.) Corda)’nun İnsan Periferal Kan Lenfositlerine Karşı Sitotoksik ve Genotoksik Aktivitesi

Abstract

Pale Liverwort-Chiloscyphus polyanthos is one of the most common aquatic liverworts that growing in or near the watering streams and lakes. It typically formed extensive matting appearance in the water or on the boulders in the water. In this study, Chiloscyphus polyanthos collected from the Erciyes Mountain were extracted using ethyl acetate, methanol, and water-methanol solvents. Cytotoxic and genotoxic effects of extracts against human peripheral blood lymphocytes were investigated. The genotoxic activity was determined by using the Chromosome Aberration Test. The cytotoxic activities of the extracts were determined by the Mitotic index (MI). The results showed that the extracts had cytotoxic effect and not genotoxic effect. According to this result, we estimate that Chiloscyphus polyanthos can be used as medicinal plant.