Turkish Neonatal Society Guideline on fluid and electrolyte balance in the newborn

Yapıcıoğlu, Hacer; Demirel, Nihal; İnce, Zeynep

doi:10.5152/turkpediatriars.2018.01807

Cited by 6 publications

(6 citation statements)

References 12 publications

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“…Weight loss of 5-10% of birth weight in term newborns and 10-15% of birth weight in preterm infants is expected and necessary in the first week of life, depending on the degree of maturation. The daily weight loss should be 1-2 percent of body weight in term newborns and 2-3 percent of body weight in preterm infants when planning maintenance fluid treatment [15].…”

Section: Body Weightmentioning

confidence: 99%

“…However, there was a weak association between urine density and osmolality as determined by pee sticks. It's important to remember that high urine density can be caused by glucose or protein in the urine of ill premature newborns [15].…”

Section: Urine Production and Densitymentioning

confidence: 99%

“…Increased water loss, insufficient water intake, and high salt consumption are the three primary causes of hypernatremia [6] .Hyponatremia is defined as a sodium level in the blood that is less than 135 milliequivalents per litre. Although a blood sodium level of less than 130 mEq/ L is commonly used to identify hyponatremia, studies in newborns reveal that hyponatremia is an independent predictor of poor neuromotor development [15].…”

Section: Hypernatremia and Hyponatremiamentioning

confidence: 99%

“…Intravenous infusion treatment aims to keep you hydrated while allowing you to lose weight naturally. The amount of maintenance fluids can be raised or lowered depending on the baby's particular needs [15]. Maintenance (IWL + urine + stool water) plus growth needs equal total fluid requirements.…”

Section: Total Fluid Requirementsmentioning

confidence: 99%

“…If the newborn displays shock signs such lethargy, circulatory collapse, prolonged capillary refill time (> 3 sec), oliguria, hypotension, or anuria, 10-20 mL/kg 0.9 percent NaCl should be administered within 10-20 minutes. This dose may be repeated if symptoms persist [15].…”

Section: Symptoms Of Hypovolemic Shock In Newborn Newborns With Hypernatremiamentioning

confidence: 99%

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Overview on Fluid, Electrolyte and Nutrition Management of the Newborn and Pre-term Newborns

Alzahrani

Altaf

Alharbi

et al. 2021

JPRI

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Often in extremely preterm newborns in the early postnatal daysproblems in fluid and electrolyte balance occur Due to excessive insensible water loss and renal immaturity. The dietary care of newborn newborns is challenged by the demands of growth and organ development. The stress of a serious disease makes it much more difficult to get enough nourishment. Newborns andespecially premature newborns must be assessed thoroughly for fluid and electrolytes balance. Calculating the fluid and electrolyte demand for sustaining metabolic activities, replacing losses (evaporative, third space, external), and considering pre-existing fluid imbalance are all part of effective fluid and electrolyte management. When a neonate's size or condition prevents them from receiving enteral nutrition, parenteral nutrition can help them grow and thrive. Although eating through the gastrointestinal tract is the recommended method of nutritional management, some situations necessitate the use of PN as an adjuvant or sole treatment. In this article we discuss fluid electrolytes and Nutritional management using parenteral nutrition.

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Section: Body Weightmentioning

confidence: 99%

Section: Urine Production and Densitymentioning

confidence: 99%

Section: Hypernatremia and Hyponatremiamentioning

confidence: 99%

Section: Total Fluid Requirementsmentioning

confidence: 99%

Section: Symptoms Of Hypovolemic Shock In Newborn Newborns With Hypernatremiamentioning

confidence: 99%

See 3 more Smart Citations

Overview on Fluid, Electrolyte and Nutrition Management of the Newborn and Pre-term Newborns

Alzahrani

Altaf

Alharbi

et al. 2021

JPRI

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Hypernatremia in Newborns: A Practical Approach to Management

2022

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Hypernatremia is a potentially serious condition in both term and preterm babies, which can lead to severe and permanent neurological damage. There are many physiological changes in sodium homeostasis that occur soon after birth. Understanding this physiological process, early anticipation of hypernatremia and familiarization with the neonatal management of hypernatremia can prevent mortality and long-term morbidity associated with this condition. This review aims to provide a practical and understandable approach to the diagnosis and management of hypernatremia in neonates.

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The efficacy and safety of isotonic and hypotonic fluids in intravenous maintenance fluid therapy in term newborns: national multicenter observational “neofluid” study

Ozkan,

Duman,

Tuzun

et al. 2024

Front. Nutr.

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ObjectiveThe objective of this study was to evaluate the efficacy and safety of isotonic and hypotonic intravenous fluids in maintenance fluid therapy for term infants.MethodsThis was a multi-centre, prospective, observational study conducted in 21 participating centres from December 30, 2020, to June 30, 2023. The study included term newborns requiring parenteral fluid therapy for maintenance (NCT04781361). The fluid treatment was divided into two groups based on the concentration of sodium in the parenteral fluid, designated as hypotonic (NaCl <130 mmol/L) and isotonic (NaCl = 130–154 mmol/L). The primary outcomes were the change in mean plasma sodium (pNa) levels per hour (∆pNa mmol/L/h), the incidence of hyponatremia (pNa <135 mmol/L) and hypernatremia (pNa >145 mmol/L), and the occurrence of clinically significant changes in sodium levels (∆pNa >0.5 mmol/L/h).ResultsA total of 420 patients from 21 centers were included. The ∆pNa was negative in the hypotonic fluid group and positive in the isotonic fluid group, with a significant difference between the groups [respectively −0.07 ± 0.03 (95% CI: −0.13 to −0.02); 0.04 ± 0.03 (95%CI: −0.02 to 0.09), p = 0.04]. There was no difference between the groups in terms of the development of hypernatremia or a clinically meaningful pNa increase. The hypotonic fluid group had a higher incidence of hyponatremia and a clinically meaningful sodium decrease compared to the isotonic fluid group [7.9% vs. 1.2% (OR:6.5, p:0.03)] and [12.2% vs.4.2% (OR:2.9, p = 0.03)].ConclusionContrary to current understanding, this large-scale study is the first to demonstrate that the use of hypotonic fluids in maintenance fluid therapy for newborns poses a risk of hyponatremia development, whereas isotonic fluid therapy appears safe.

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Turkish Neonatal Society Guideline on fluid and electrolyte balance in the newborn

Cited by 6 publications

References 12 publications

Overview on Fluid, Electrolyte and Nutrition Management of the Newborn and Pre-term Newborns

Overview on Fluid, Electrolyte and Nutrition Management of the Newborn and Pre-term Newborns

Hypernatremia in Newborns: A Practical Approach to Management

The efficacy and safety of isotonic and hypotonic fluids in intravenous maintenance fluid therapy in term newborns: national multicenter observational “neofluid” study

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