Türkiye’de İnsanlarda Kistik Ekinokokkoz

Ok, Ülgen Z.; Kilimcioğlu, Ali Ahmet; Özkol, Mine

doi:10.5578/mb.69712

Cited by 12 publications

(7 citation statements)

References 16 publications

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“…Also most of the clinics dealing with this problem present a treatment analysis of a small number of observations. This is due to a rather low frequency of surgical operations performed for this pathology ( 10 – 12 ).…”

Section: Discussionmentioning

confidence: 99%

Clinical, Morphological Justification and First Experience in the Use of Radiofrequency as well as Microwave Ablation Treatment Methods of Liver Echinococcosis

Шабунин¹,

Karpov²,

Bedin³

et al. 2023

IJPA

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Background: The current study considers a new direction of surgical treatment of liver echinococcosis - the use of minimally invasive treatment methods of parasitic cysts. Methods: After clinical and morphological substantiation of the very possibility of carrying out such procedures, 9 microwave ablations (MWA) and 3 radiofrequency ablations (RFA) of cysts were performed in patients with liver echinococcosis from 2017 to 2021 in the surgical clinic of Botkin Hospital, Moscow, Russia. A comparative analysis of treatment results of patients with echinococcal liver cysts (12 patients who underwent “percutaneous puncture, aspiration, injection and reaspiration” (PAIR) procedure and 12 patients – MWA and RFA) was carried out. Results: The number of complications according to Clavien-Dindo classification was as follows: 8 after PAIR procedure, 3 after RFA and 3 after MWA. The median hospital length of stay (LOS) after PAIR procedure was 6.46 days versus 4.7 and 4 in the groups of patients who underwent RF and MW ablation, respectively. The frequency of relapses within the first year after PAIR procedure was 25%. The patients who underwent ablation procedures had no relapses of liver echinococcosis during observation. Conclusion: The presented clinical and morphological substantiation and the experience of using various types of ablation techniques on echinococcal cysts, as well as a comparative analysis with a commonly used PAIR treatment method, demonstrated the safety of RFA and MWA for the patient and efficacy in relation to the hydatid process.

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Section: Discussionmentioning

confidence: 99%

Clinical, Morphological Justification and First Experience in the Use of Radiofrequency as well as Microwave Ablation Treatment Methods of Liver Echinococcosis

Шабунин¹,

Karpov²,

Bedin³

et al. 2023

IJPA

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“…Dünyada bir milyon kişinin KE ile enfekte olduğu düşünülmektedir (15) . Ülkemizde yapılan tarama çalışmalarından yola çıkılarak, prevalansın %0.5-0.6 olduğu ve yaklaşık her 150.000-200.000 kişiden birinin etken ile enfekte olduğu tahmin edilmektedir (8,16) . Ülkemiz ve dünya için oldukça önemli bir halk sağlığı sorunu olan KE'nin tanısında; başlangıç semptomlarının nonspesifikliği nedeniyle akla gelmemesi ve testlerde duyarlılığın düşük olabilmesi nedeniyle gecikmeler yaşanabilmektedir.…”

Section: Discussionunclassified

Use of Indirect Hemagglutination Test in the Diagnosis of Cystic Echinococcosis: Two Years of Retrospective Laboratory Experience

Bağcı¹,

Pektaş²,

Gökmen³

et al. 2022

Turk Mikrobiyol Cemiy Derg

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“…According to the data of WHO, worldwide, CE causes about 19,300 deaths per year [ 5 ]. The exact number of all CE cases is difficult to estimate in Türkiye because data on the prevalence of CE in Türkiye is based on screening studies involving a small and limited number of population and cases usually reported by hospital records [ 6 ]. A study under the Heracles (Human cystic echinococcosis ReseArch in CentraL and Eastern Societies) Project investigated rural areas of Bulgaria, Romania, and Türkiye by ultrasound-based screening.…”

Section: Introductionmentioning

confidence: 99%

“…In the study, abdominal CE was found in 53 (0.6%) of the total of 8618 people in villages belonging to six provinces of Türkiye. It is known that this study is the most comprehensive screening in Türkiye to date [ 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

Comparison of Methods in the Serologic Diagnosis of Cystic Echinococcosis

Erganis,

Sarzhanov,

et al. 2024

Acta Parasit.

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Purpose Cystic echinococcosis (CE) is caused by the larval form of Echinococcus granulosus. Clinical, radiologic, pathologic, and serologic findings should be evaluated together for the diagnosis of CE. The sensitivity and specificity oalf serologic tests may vary depending on the method used. In this study, we aimed to detect IgG antibodies specific to E. granulosus using indirect hemagglutination assay (IHA), enzyme-linked immunosorbent assay (ELISA), indirect fluorescent antibodies (IFA) and western blot (WB) tests. Methods In our study, the serum samples of 74 patients sent to our laboratory with suspicion of CE were studied using two different commercial IHA tests, ELISA, IFA and WB test. The test results were evaluated along with radiological findings and histopathological examinations, the latter being the gold standard. Results Of all the patients, 51 (69%) were female and 23 (31%) were male. There was a statistically significant difference between males and females (χ2 = 9.7, p = 0.002). Out of 74 patients, positivity rates for Siemens IHA, Fumouze IHA, ELISA, IFA and WB test were positive as 33 (44.6%), 35 (47.3%), 43 (58.1%), 42 (56.7%) and 38 (51.3%), respectively. The sensitivity and specificity of the tests were as follows: 66.67 and 2.31% for Siemens IHA; 70.83% and 96.15% for Fumouze IHA; 85.42%, and 88.46% for ELISA; 83.33% and 88.46% for IFA; 72.92% and 88.46% for WB test. Conclusion There were statistically significant differences in between all five methods (p < 0,001). While the tests with the highest specificity was Fumouze IHA, the test with the highest sensitivity was the ELISA test. It was concluded that IHA and ELISA tests were more practical in practice because of their greater applicability.

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Türkiye’de İnsanlarda Kistik Ekinokokkoz

Cited by 12 publications

References 16 publications

Clinical, Morphological Justification and First Experience in the Use of Radiofrequency as well as Microwave Ablation Treatment Methods of Liver Echinococcosis

Clinical, Morphological Justification and First Experience in the Use of Radiofrequency as well as Microwave Ablation Treatment Methods of Liver Echinococcosis

Use of Indirect Hemagglutination Test in the Diagnosis of Cystic Echinococcosis: Two Years of Retrospective Laboratory Experience

Comparison of Methods in the Serologic Diagnosis of Cystic Echinococcosis

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