Turmeric: Reemerging of a Neglected Asian Traditional Remedy

Khajehdehi, Parviz

doi:10.5812/jnp.5

Cited by 61 publications

(44 citation statements)

References 35 publications

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“…Vegetables, fruits and their juices contain phenolic compounds, which have antioxidant properties and are protective against atherosclerosis. [3132]…”

Section: Discussionmentioning

confidence: 99%

Acute effects of vinegar intake on some biochemical risk factors of atherosclerosis in hypercholesterolemic rabbits

et al. 2010

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BackgroundExaggerated postprandial spikes in blood glucose and lipids induce proportional increases in oxidative stress, which acutely trigger impairment endothelial, inflammation and increased risk of future cardiovascular events. In this research, we have investigated acute effects of vinegar intake on some of the biochemical atherosclerosis risk factors in high cholesterol fed rabbits to see if we can find a probable protective value for it.MethodsThe rabbits were randomly divided into four groups: normal diet, high cholesterol diet (%1cholesterol), %1 cholesterol with 5 ml vinegar (low dose), %1 cholesterol with 10 ml vinegar (high dose). After fasting for 12-15 hours, blood samples were taken to determine baseline values. Three hours after feeding, blood samples were collected again to investigate acute effects of vinegar intake on the measured factors.ResultsUsing high-dose vinegar with cholesterolemic diet caused significant reduce in LDL-cholesterol (LDL-C), oxidized-LDL (ox-LDL), malondialdehyde (MDA), total cholesterol (TC) and apolipoprotein B (ApoB) in comparison with hypercholesterolemic diet. Consumption low-dose vinegar with cholesterolemic diet induced a significant decrease in fibrinogen and glucose compared to hypercholesterolemic diet. Level of serum nitrite, nitrate, triacylglycerol (TAG), HDL-cholesterol (HDL-C), apolipoprotein A (ApoA), serum glutamic pyruvic transaminase (SGPT), serum glutamic oxaloacetate transaminase (SGOT) and C-reactive protein (CRP) were not significantly difference in low and high doses vinegar with cholesterolemic diet compared to hypercholesterolemic diet. A significant difference was observed for LDL-C, ApoB100 and TC between low and high doses vinegar.ConclusionThis study suggest that vinegar, might have some acute effects on biochemical risk factors of atherosclerosis and a probable protective value can be considered for its postprandial use.

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“…Vegetables, fruits and their juices contain phenolic compounds, which have antioxidant properties and are protective against atherosclerosis. [3132]…”

Section: Discussionmentioning

confidence: 99%

Acute effects of vinegar intake on some biochemical risk factors of atherosclerosis in hypercholesterolemic rabbits

et al. 2010

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“…The mortality rate of patients with ARF is remained 25-70%, despite the use of various pharmacologic agents (2)(3)(4)(5). Indeed, ARF frequently occurs in critically ill patients and is an independent risk factor for poor outcome.…”

Section: Introductionmentioning

confidence: 99%

Erythropoietin ameliorates genetamicin-induced renal toxicity: A biochemical and histopathological study

et al. 2012

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Background:Investigations have attempted to modify the outcome of tubular injury by either ameliorating renal tubular damage or promoting tubular regeneration in the case of acute tubular necrosis. Objectives: We investigated the protective effect of Eprex an erythropoietin analogue on tubular injury induced by gentamicin (GM). Materials and Methods: Forty male Wistar rats were randomly divided into four groups. In group 1,rats were served as a sham group. In group 2, rats were injected intraperitoneally with 100 mg/kg of GM for 10 consecutive days (positive control group) and then were sacrificed. In group 3, rats received GM for 10 days then Eprex 100U/kg was injected intraperitoneally for the next 10 days and then they were sacrificed at the day 20th. In group 4 rats were injected a combination of GM (80 mg/kg) and Eprex 100U/kg intraperitoneally for 10 days and then were sacrificed. Results: The results indicated that, Eprex prevented the increase in serum creatinine (Cr) and blood urea nitrogen (BUN). The effect of Eprex on damage score, showed that co-administration of GM and Eprex (group 3 and 4) reduced the kidney tissue damage compared to positive control group (P<0.05). This result indicat that Eprex potentially can reduce or prevent the kidney tissue damage. Conclusions: Ameliorative effect of Eprex when the drug was given in combination with GM and also when the drug was applied after GM-induced tubular damage, revealed the renoprotective potency of Eprex. Eprex is a promising drug to prevent or attenuate tubular damage induced by GM or other nephrotoxic agents which act through the same mechanisms as gentamicin.

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“…We concluded that Teucrium polium may be associated with kidney tubular injury and that this herbal medicine should be used with caution [2]. It is well known that herbal remedies have an important role in the recovery of some disease [6–9]; however, some medicinal plants can cause renal injury. Teucrium polium has been widely used to control blood sugar in diabetes [7].…”

mentioning

confidence: 99%

Comment on: Preventive effect of Teucrium polium on learning and memory deficits in diabetic rats

Rafieian-Kopaei

Nasri

2013

Med Sci Monit Basic Res

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Turmeric: Reemerging of a Neglected Asian Traditional Remedy

Abstract: considering the inhibitory effect of turmeric/curcumin on cytokines and TGF-β, it seems wise to assume that supplementary turmeric/curcumin might be a candidate remedy for chronic kidney disease and possibly prevention of subsequent end stage renal disease.

Cited by 61 publications

References 35 publications

Acute effects of vinegar intake on some biochemical risk factors of atherosclerosis in hypercholesterolemic rabbits

Acute effects of vinegar intake on some biochemical risk factors of atherosclerosis in hypercholesterolemic rabbits

Erythropoietin ameliorates genetamicin-induced renal toxicity: A biochemical and histopathological study

Comment on: Preventive effect of Teucrium polium on learning and memory deficits in diabetic rats

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