Turntable for Exercising Rats

Farris, Edmond J.; Engvall, Gustav

doi:10.1126/science.90.2328.144

Science

1939

DOI: 10.1126/science.90.2328.144

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Turntable for Exercising Rats

Edmond J. Farris

Gustav Engvall

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1941

1966

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Apparatus for recording cyclical activity in the rat

Farris

1941

Anat. Rec.

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In connection with studies on the effects of neuro-physiological (emotional) stimuli on life processes of the rat, it was necessary to develop an apparatus for determining accurately the normal peak, regularity and length of the estrous cycle. It was important to eliminate as nearly as possible all stimuli that had been observed to, or may probably, cause physiological (emotional) upsets, such as daily handling in routine care, reading cage cyclometers periodically, making vaginal smears, testing copulatory response, disturbances by illumination, and transferring of rats frequently into various drums from reguular cages.Wang ('23) showed the activity cycle bears an intimate relation to the estrous rhythm, the female rat being most active in the period of estrus. By means of vaginal smears and mating tests Slonaker ('24) showed the peak in activity curve corresponds and is identical with the cornified cell stage and at this time the female readily accepts the male. He states as well in .his excellent article that, "Our experiments seem to indicate that making of vaginal smears, due to the necessary handling, etc., of the animal, tends to disturb the regularity of oestruation. We feel therefore that normal sequence is more accurately shown by activity curves than by any other method advanced, as it leaves the animal undisturbed by unavoidably varying conditions." Allen ( '39) quotes Wang This inwstigation was nidcd by a grant from the Samuel S. Fcls Fund. 357

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Apparatus for recording cyclical activity in the rat

Farris

1941

Anat. Rec.

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Spontaneous activity of animals; a review of the literature since 1929.

Jd¹

1947

Psychological Bulletin

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Biological Assessment of Tranquillisers. Part I

Riley¹,

Spinks²

1958

Journal of Pharmacy and Pharmacology

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Turntable for Exercising Rats

Cited by 4 publications

References 0 publications

Apparatus for recording cyclical activity in the rat

Apparatus for recording cyclical activity in the rat

Spontaneous activity of animals; a review of the literature since 1929.

Biological Assessment of Tranquillisers. Part I

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