2024
DOI: 10.1038/s42005-024-01606-9
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Tutorial: a beginner’s guide to building a representative model of dynamical systems using the adjoint method

Leon Lettermann,
Alejandro Jurado,
Timo Betz
et al.

Abstract: Building a representative model of a complex dynamical system from empirical evidence remains a highly challenging problem. Classically, these models are described by systems of differential equations that depend on parameters that need to be optimized by comparison with data. In this tutorial, we introduce the most common multi-parameter estimation techniques, highlighting their successes and limitations. We demonstrate how to use the adjoint method, which allows efficient handling of large systems with many … Show more

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