Tween emulsifiers improved alginate-based dispersions and ionic crosslinked milli-sized capsules

Zheng, Yulu; Zi, Ye; Shi, Cuiping; Gong, Hongyu; Zhang, Hongbin; Wang, Xichang; Zhong, Jian

doi:10.1038/s41538-023-00208-z

Cited by 9 publications

(1 citation statement)

References 41 publications

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“…However, for the microcapsules obtained by emulsion, the differences (p < 0.05) observed in the water content may be due to the other factors evaluated, thus the capsules with lower moisture are obtained by emulsion with a stirring speed of 600 ppm for 10 min, either with 2% (T11) or 4% lactulose (T15). The moisture values in these treatments are like those in other studies (50-60%) with alginate-Tween capsules [39]. The treatments that were found to be less moisture could be good candidates to keep LAB alive, since by reducing the water that interacts with the bacteria, their metabolic processes can be slowed down and their stability increased [40], without resorting to expensive processes of spray drying or freeze drying.…”

Section: Moisturesupporting

confidence: 65%

Use of Lactulose as Prebiotic and Chitosan Coating for Improvement the Viability of Lactobacillus sp. FM4.C1.2 Microencapsulate with Alginate

Rizo-Vázquez,

Vázquez-Ovando,

Mejía-Reyes

et al. 2024

Processes

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Lactic acid bacteria (LAB) constitute the microbial group most used as probiotics; however, many strains reduce their viability during their transit through the body. The objective of this study was to evaluate the effect of two microencapsulation techniques, as well as the incorporation of lactulose as a prebiotic and the use of chitosan coating on the microcapsules, on the viability of the Lactobacillus sp. strain FM4.C1.2. LAB were microencapsulated by extrusion or emulsion, using 2% sodium alginate as encapsulating matrix and lactulose (2 or 4%) as the prebiotic. The encapsulation efficiency was evaluated, and the capsules were measured for moisture and size. The encapsulation efficiency ranged between 80.64 and 99.32% for both techniques, with capsule sizes between 140.64 and 1465.65 µm and moisture contents from 88.23 to 98.04%. The microcapsules of some selected treatments (five) were later coated with chitosan and LAB survival was evaluated both in coated and uncoated microcapsules, through tolerance to pH 2.5, bile salts and storage for 15 days at 4 °C. The highest survival of the probiotic strain under the conditions of pH 2.5 (96.78–99.2%), bile salts (95.54%) and storage for 15 days (84.26%), was found in the microcapsules obtained by emulsion containing 4% lactulose and coated with chitosan. These results demonstrate the possible interaction of lactulose with alginate to form better encapsulating networks, beyond its sole probiotic effect. Additional research may shed more light on this hypothesis.

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Section: Moisturesupporting

confidence: 65%

Use of Lactulose as Prebiotic and Chitosan Coating for Improvement the Viability of Lactobacillus sp. FM4.C1.2 Microencapsulate with Alginate

Rizo-Vázquez,

Vázquez-Ovando,

Mejía-Reyes

et al. 2024

Processes

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Oxidative stability of optimized nanostructured lipid carriers containing thymoquinone‐rich oil

Ardhi,

Raharjo,

Sudjarwo

et al. 2024

J Americ Oil Chem Soc

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Lipid‐based nanodelivery systems are now widely used in the pharmaceutical and food industries to enhance the delivery of bioactive compounds by leveraging the properties of lipids. Nanostructured lipid carriers (NLC), as one of the lipid‐based nano‐delivery systems, employs a blend of solid and liquid lipids, which improves the solubility, stability, and bioavailability of bioactive substances. This study aimed to optimize the NLC containing thymoquinone‐rich oil (NLC‐TQO) formulation using the Box–Behnken design; assess its antioxidant activity and oxidative stability by measuring 2,2‐diphenyl−1‐picrylhydrazyl (DPPH) radical scavenging activity, thymoquinone (TQ), and tocopherol contents over 28‐day storage; and evaluate the impact of incorporating beta‐carotene as singlet oxygen quencher on the oxidative stability of the NLC‐TQO. The optimized formulation involved 4.16% lipids (glyceryl monostearate and TQO), 5.85% Tween 80 as the surfactant, and 8.20 min of ultrasonication. NLC formulations demonstrated better DPPH activity retention than the emulsions, with cold and dark storage conditions being the most effective for preserving antioxidant activity. TQ stability in the NLC was observed at elevated temperatures without light, with around 50% remaining intact. However, TQ degraded rapidly under light, almost entirely by day 7. Gamma‐tocopherol exhibited better stability than alpha‐tocopherol, especially under light. The addition of beta‐carotene enhanced NLC‐TQO's oxidative stability. These findings revealed the potential of the NLC formulation as an effective delivery system for TQ with better oxidative protection compared to emulsions, making it a promising option for pharmaceutical and food industry applications.

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Stability and antioxidant properties of freeze-concentrated acerola juice in water-in-oil-in-water emulsions

Dang,

Tran,

Kha

2024

Applied Food Research

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Tween emulsifiers improved alginate-based dispersions and ionic crosslinked milli-sized capsules

Cited by 9 publications

References 41 publications

Use of Lactulose as Prebiotic and Chitosan Coating for Improvement the Viability of Lactobacillus sp. FM4.C1.2 Microencapsulate with Alginate

Use of Lactulose as Prebiotic and Chitosan Coating for Improvement the Viability of Lactobacillus sp. FM4.C1.2 Microencapsulate with Alginate

Oxidative stability of optimized nanostructured lipid carriers containing thymoquinone‐rich oil

Stability and antioxidant properties of freeze-concentrated acerola juice in water-in-oil-in-water emulsions

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