Twelve months of experience with Bioplastique

Abstract

Over a 12-month period, 40 patients were treated for various facial defects using a new, injectable microimplant material--Bioplastique. Areas treated included cheeks, chins, lips, nasolabial lines, nasoglabellar lines, infraoral lines, noses, and miscellaneous depressions. Patients were observed for overcorrection, inflammation, morbidity, allergic reaction, or other complications. Both patient and physician satisfaction were recorded. Use of Bioplastique was found to offer permanent results by means of a quick, simple procedure administered under local anesthesia without scarring. With proper training and a good "eye," subtle corrections are possible. The author anticipates wide application of Bioplastique for the treatment of numerous soft tissue deficiencies.

A comparative experimental study of silicone gel and bioplastique

“…The sequence of events in the host immune system is consistent with that found in other benign implant systems. There are several reports that the largest is 65 micron in lymph nodes with silicone injection [2,14,17]. However, 24 h after injection the reaction showed a small number of neutrophils and numerous other inflammatory cells.…”

“…The collagen remains and forms a three-dimensional lattice work around the particles leading to the permanance of soft tissue correction [8,14]. The net quantity of collagen stabilized with collagen synthesis and degradation in apparent equilibrium.…”

“…They are freely transported through tissue fluids and excreted unchanged by the kidneys [8,14,17]. The hydrogel is of the family of plasdones, having average molecular weigth of approximately 13,700.…”

An Experimental Study of Tissue Reaction to Polymethyl Methacrylate (PMMA) Microspheres (Artecoll) and Dimethylsiloxane (DMS) in the Mouse

“…These findings have also been seen in animal and human models. [12][13][14][15][16] The weight differences between the ears provided a parameter to analyze the intensity of tissue reaction to the injected material. The weight difference was smallest at the beginning of the study, becoming more evident by the eighth week, around the same time as the absorption of the transport vehicle, 3.5% bovine collagen.…”

Removal of bioplastique after nasal augmentation

“…Bioplastique has given good results in treating various facial soft tissue defects [4,6,7]. Some complications have been reported, including glabellar overcorrection [6,7], infraorbital overcorrection [6], small palpable aggregates in lip augmentation [3,5], and small palpable aggregates beneath the eyes at the junction of the lower eyelid and the infraorbital rim [3].…”