Twenty-Eight

Krishnan, Mini; Sen, Nabaneeta Dev; Dalal, Suresh; Ratan, Jai; Sharma, Ramachandra; George, K. M.; Paranjape, Makarand; Das, Manoj; Maini, Darshan Singh; Indra, C. T.; Rao, Ranga; Komal, Balraj

doi:10.1007/978-1-349-15111-0_28

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Polymeric Nanocarriers1

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2020

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“…In terms of tumor growth, the 100 nm diameter particles were slightly better than those with 50 or 150 nm diameters, but the most toxic effects to healthy tissue were observed for the smaller particles. This phenomenon was maybe caused by enhanced permeability of normal tissue blood vessels as result of radiation, [48] which Figure 3. a) Schematic drawing of the mesoporous silica nanocarriers and the proposed mechanism of targeting to the nucleus, b) their structure as obtained by Scanning Electron Microscopy (SEM), and c) element mappings revealing the different elements (i.e., Y, F, Yb, and Gd) enclosed in the nanostructures.…”

Section: Polymeric Nanocarriersmentioning

confidence: 99%

Enhanced Cancer Therapy by Combining Radiation and Chemical Effects Mediated by Nanocarriers

Denkova

Liu

Men

et al. 2020

Advanced Therapeutics

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Next to surgery, radiotherapy and chemotherapy are the two most commonly applied treatments against cancer. These therapies are often combined, but the therapeutic outcome is still limited. Nanocarriers may be the solution to many of the issues encountered when combining these therapies. In this review, the role of nanocarriers in combined radiotherapy and chemical cancer treatment is discussed, divided into four distinct strategy classes. For each strategy, examples of the literature are given to come eventually to conclusion on the possible translation to the clinic.

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Section: Polymeric Nanocarriersmentioning

confidence: 99%