Twenty-four hour ambulatory blood pressure reference values in Africans

Bawa-Allah, Abdulraheem; Mashao, Mercy; Nyundu, Thamsanqa; Phukubje, Edgar; Mlambo, Bongubuhle; Нгема, М В; Nkosi, B. G.; Maseko, Muzi J.

doi:10.1097/mbp.0000000000000376

Cited by 1 publication

(1 citation statement)

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“…[14][15][16] In sub Saharan Africa, interest is growing in ABPM, as evidenced by several recent publications from the region, both from hospital settings and in the general population, [17][18][19][20][21][22] and even cut-off points for ABPM have been suggested for people in sub Saharan Africa. 23 A recent meta-analysis found the prevalence of white coat and masked hypertension to be high (11% and 14.8%, respectively), especially among urban dwellers across Africa, and recommended the use of out-of-office BP measurements to detect people with these conditions. 24 However, data on ABPM are still missing in Tanzania, where only one previous study has been carried out among 79 elderly (>70 years) citizens in Northern Tanzania.…”

Section: Introductionmentioning

confidence: 99%

Ambulatory Blood Pressure Profiles and Correlation with Cardiovascular Risk Factors in a Sample of 390 University Employees in Tanzania

Chuwa

Chillo

2020

IBPC

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Background Hypertension is a major risk factor for cardiovascular morbidity and mortality. Increasingly, evidence suggests that 24-hour ambulatory blood pressure (BP) monitoring (ABPM) is more accurate than clinic BP in predicting cardiovascular risk. However, this association has not been widely studied in subSaharan Africa, especially in Tanzania. Aim To explore the relationship between 24-hour ABPM profiles and cardiovascular risk factors in comparison with clinic BP among Muhimbili University of Health and Allied Sciences (MUHAS) employees. Methods A descriptive cross-sectional study was conducted from October 2018 to February 2019. Socio-demographic and cardiovascular risk information was gathered. We used an automated ABPM device to record 24-hour ambulatory BP. Correlation between BP profiles and cardiovascular risk factors was done using Pearson’s correlation coefficient, and independent factors for hypertension were determined using logistic regression analysis. P -value of <0.05 was considered statistically significant. Results In total, 390 employees participated. Their mean age was 40.5 ± 8.9 years, and 53.6% were men. The mean office systolic and diastolic BP were 126±12 mmHg and 78±13 mmHg, respectively, while the corresponding values for mean 24-hour ABPM were 122±14 and 75±10 mmHg. The prevalence of hypertension was 23.1%. The prevalence of white coat hypertension was 16.2%, while masked hypertension and nocturnal non-dipping were present in 11.5 and 66.7%, respectively. Overall, the mean 24-hour systolic BP showed the strongest correlations with cardiovascular risk factors while mean office systolic BP showed least. Independent associated factors of hypertension were male gender, age ≥40 years, family history of hypertension, central obesity, raised cholesterol and uric acid levels, all p<0.01. Conclusion Compared to office BP, ABPM measurements had stronger correlations with cardiovascular risk factors in this population, and therefore likely to reflect true BP. ABPM has revealed high proportion of masked, white coat and nocturnal non-dipping, supporting use of ABPM to detect these clinically important BP profiles.

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