Twenty-Four-Hour Electrocardiographic Study in the Active Very Elderly

Rossi, Alessandro

doi:10.1159/000174192

Cited by 12 publications

(5 citation statements)

References 14 publications

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“…The frequency and prevalence of PACs are known to increase with age. 29 As with PVCs, differences in study populations (older male), detection methods (24-hour monitoring) and outcomes (composite stroke) may explain this discrepancy.…”

Section: Discussionmentioning

confidence: 99%

“…The prevalence of PACs in that study was 19% compared to 4.9% in our study, while the stroke rate was 14% compared to 3.5% in our study. The frequency and prevalence of PACs are known to increase with age . As with PVCs, differences in study populations (older male), detection methods (24‐hour monitoring) and outcomes (composite stroke) may explain this discrepancy.…”

Section: Discussionmentioning

confidence: 99%

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Premature Cardiac Contractions and Risk of Incident Ischemic Stroke

Ofoma

Shaffer

et al. 2012

JAHA

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BackgroundThe etiologies of ischemic stroke remain undetermined in 15% to 40% of patients. Apart from atrial fibrillation, other arrhythmias are less well-characterized as risk factors. Premature cardiac contractions are known to confer long-term cardiovascular risks, like myocardial infarction. Ischemic stroke as cardiovascular risk outcome remains a topic of interest. We examined the prospective relationships in the Atherosclerosis Risk in Communities (ARIC) study, to determine whether premature atrial (PAC) or ventricular (PVC) contractions are associated with increased risk for incident ischemic stroke.Methods and ResultsWe analyzed 14 493 baseline stroke-free middle-aged individuals in the ARIC public-use data. The presence of PAC or PVC at baseline was assessed from 2-minute electrocardiogram. A physician-panel confirmed and classified all stroke cases. Average follow-up time was 13 years. Proportional hazards models assessed associations between premature contractions and incident stroke. PACs and PVCs were identified in 717 (4.9%) and 793 (5.5%) participants, respectively. In all, 509(3.5%) participants developed ischemic stroke. The hazard ratio (HR) (95% confidence interval [CI]) associated with PVC was 1.77 (1.30, 2.41), attenuated to 1.25 (0.91, 1.71) after adjusting for baseline stroke risk factors. The interaction between PVC and baseline hypertension was marginally significant (P=0.08). Among normotensives, having PVCs was associated with nearly 2-fold increase in the rate of incident ischemic stroke (HR 1.69; 95% CI 1.02, 2.78), adjusting for stroke risk factors. The adjusted risk of ischemic stroke associated with PACs was 1.30 (95% CI 0.92, 1.83).ConclusionsPresence of PVCs may indicate an increased risk of ischemic stroke, especially in normotensives. This risk approximates risk of stroke from being black, male, or obese in normotensives from this cohort.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Premature Cardiac Contractions and Risk of Incident Ischemic Stroke

Ofoma

Shaffer

et al. 2012

JAHA

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“…Fleg et al [18] reported a PVC prevalence of 78% among 98 healthy people aged 60-85 years. Higher rates were reported in older groups, reaching 89.4% in a study by Garcia et al [19] including 94 healthy subjects aged 70 years and older, 96% in a study by Kantelip et al [20] in 50 people aged 80 years and older, and 100% in a study by Rossi et al [17] including 18 active subjects aged 90 years and older.…”

Section: Discussionmentioning

confidence: 91%

“…The prevalence of PVC in the general population ranges from 4 to 20% and increases with age [14,15]. Studies conducted among active older people have shown that the prevalence of PVC varies 69-100% [16,17]. Fleg et al [18] reported a PVC prevalence of 78% among 98 healthy people aged 60-85 years.…”

Section: Discussionmentioning

confidence: 99%

“…Our study also showed that the prevalence of PVC was higher in patients with reduced ejection fraction, consistent with the literature data. In addition, the presence of ventricular arrhythmias in patients with low ejection fraction is associated with high cardiac mortality [17]. Increased LVEDD is an indicator of left ventricular dilation, which leads to arrhythmias via various mechanisms.…”

Section: Discussionmentioning

confidence: 99%

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Cardiac arrhythmias in geriatric patients receiving palliative care support

Taşar,

Karasahin,

Birdal

et al. 2023

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Introduction:Although palliative care patients often undergo electrocardiography (ECG), a detailed cardiac examination is often skipped. The aim of this study was to determine the incidence of arrhythmia in older patients in need of palliative care and to evaluate risk factors for asymptomatic arrhythmias. Material and methods:This prospective observational study was conducted between 1 March and 1 September 2022 among inpatients in the palliative care unit of Atatürk University Faculty of Medicine Hospital. Malnutrition status was assessed using the full Mini Nutritional Assessment. Delirium was assessed at hospitalization using the confusion assessment method. Electrocardiography was performed in all patients at admission to the palliative care unit. This was followed by 12-lead, 24-hour ambulatory ECG to detect arrythmias. Electrocardiography recordings were evaluated. Results:The 100 patients included in the study had a median age of 78 years, and 63.0% were women. Arrythmias were detected on Holter ECG in 70 patients (70.0%). The most common were premature ventricular contraction (PVC) (56.5%) and atrial fibrillation (AF) (30.4%). There was a statistically significant negative moderate correlation between PVC load and left ventricular ejection fraction (r = -0.308; p = 0.002). Premature ventricular contraction load was significantly higher in men than in women (p = 0.018). Of the patients with AF, 17 (17.0%) were under anticoagulant therapy. Left ventricular ejection fraction differed significantly according to the presence of AF and anticoagulant use. Left ventricular ejection fraction was lower in patients with AF and anticoagulant use compared to those without AF (p = 0.001). Conclusions:The prevalence of arrhythmias in palliative care patients is considerable. The treatment of arrhythmias in this patient population is complicated by polypharmacy, comorbidities, and frailty.

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Ambulatory Electrocardiographic Recordings

Willis¹

2018

Guide to Canine and Feline Electrocardiography

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Twenty-Four-Hour Electrocardiographic Study in the Active Very Elderly

Cited by 12 publications

References 14 publications

Premature Cardiac Contractions and Risk of Incident Ischemic Stroke

Premature Cardiac Contractions and Risk of Incident Ischemic Stroke

Cardiac arrhythmias in geriatric patients receiving palliative care support

Ambulatory Electrocardiographic Recordings

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