Twenty-Four-Hour Electrocardiography in a Healthy Elderly Population

Andersson, Staffan; Österlind, Per Olov; Holmboe, Gerd; Windblad, Bengt

doi:10.1159/000212943

Cited by 7 publications

(3 citation statements)

References 11 publications

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“…Among the APCs group 55.5% was smoker, all the 4 COPD patient was getting sulbutamol, tablet theophylline which might have precipitated the development of APCs. 15,16 Most of them also gave history of taking tea, coffee or betal nut which also may be the precipitant.…”

Section: Discussionmentioning

confidence: 99%

Aetiological Pattern of Premature Ventricular and Atrial Complexes and their Consequence on Morbidity and Mortality

et al. 2015

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Background: Arrhythmias are often a manifestation of structural heart diseases but may occur in the context of non cardiac diseases even in an otherwise normal heart. It may be supraventricular or ventricular. Among the arrhythmias premature complexes (ventricular & atrial) are most common type of arrhythmia occurs in patients with or without significant heart disease.Objective: In this study, the aim was to find out the aetiological pattern of premature ventricular and atrial complexes and their consequence on morbidity and mortality, demographical pattern of patients with ectopic beats, to find out aetiological factors leading to development of premature complexes, to find out common clinical presentations and to differentiate the PVCs which are more benignMethods: It was a cross sectional study. This study was carried out in the Department of Medicine and Department of Cardiology of Sir Salimullah Medical College and Mitford Hospital, Dhaka from 1st May 2008 to 15th September 2008. A total 50 consecutive patients irrespective of age, sex and occupation having atrial and ventricular premature complexes on ECG attending at OPD and admitted in indoor were included in this study. Results: Among the three types of premature complexes 9 patients with APCs (also includes 2 patients of premature junctional complex) and 41 patients with PVCs were included. The ratio of patients with PVCs and APCs in this study.8.2: 1.8. In this study 41 patients of PVCs were studied. Among them 37 patient that is 90.3% patients had structural heart disease and the commonest cause was IHD (63.4%), 9.7% had HTN with LVH, 7.3% had DCM, 4.87% had HOCM, one patient had myocarditis ( 2.4%) and one had MVP with sick sinus syndrome (2.4%). Among the 9 patients of APC 4 patients that is 44.44% were suffering from COPD with corpulmonale which was the most commonest cause of APCs.Conclusions: Ventricular arrhythmias are more common than atrial arrhythmia and IHD is the single most common cause of arrhythmia. Ectopic beats in patients with otherwise normal hearts are more prominent at rest and disappear with exercise. Treatment is not necessary, unless the patient is highly symptomatic.J MEDICINE July 2015; 16 (2) : 97-102

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Section: Discussionmentioning

confidence: 99%

Aetiological Pattern of Premature Ventricular and Atrial Complexes and their Consequence on Morbidity and Mortality

et al. 2015

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“…However, few studies have focused on the reference values for the prevalence of arrhythmias in each generation (younger, middle-aged, older populations) over a wide age range among healthy individuals. Previous studies on this subject included small sample sizes or were limited to fewer age groups, such as young (20-39 years) (5)(6)(7)(8)(9), middle-aged (40-59 years) (7,10,11), or older-aged cohorts (over 60 years) (7,(11)(12)(13)(14)(15)(16). Moreover, most of these studies were conducted 20-40 years prior.…”

Section: Introductionmentioning

confidence: 99%

Age-related reference intervals for ambulatory electrocardiographic parameters in healthy individuals

Hashimoto

Harada

Kimata

et al. 2023

Front. Cardiovasc. Med.

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BackgroundThe advent of novel monitoring technologies has dramatically increased the use of ambulatory electrocardiography (AECG) devices. However, few studies have conducted detailed large-scale investigations on the incidence of arrhythmias over 24 h, especially ectopy, in healthy individuals over a wide age range.ObjectivesThis study aimed to investigate the incidence of arrhythmias detected using AECG and associated factors, in healthy individuals, over a wide age range.MethodsIn this cross-sectional study, we performed AECG on 365 healthy volunteers (median [interquartile range]: 48 [36, 67], 20–89 years, 165 men) under free-running conditions for 24 h. Ultrasonic echocardiography and heart rate variability analysis were performed to explore the factors associated with the incidence of arrhythmias.ResultsThe 97.5th percentile of single ventricular ectopy (VE) was 149/day, 254/day, and 1,682/day in the 20–39-, 40–59- and 60–89-year age groups, respectively; that of single supraventricular ectopy (SVE) was 131/day, 232/day, and 1,063/day, respectively. Multivariate analysis revealed that aging was the only independent significant factor influencing the frequency of VE (β = 0.207, P = 0.001). Age (β = 0.642, P < 0.001), body mass index (BMI) (β = −0.112, P = 0.009), and the root mean square of successive differences in RR intervals (β = 0.097, P = 0.035) were factors significantly associated with SVE frequency.ConclusionsAge-specific reference intervals of VE and SVE in a large population of healthy participants over a wide age range were generated. VE and SVE increased with age; SVE was influenced by BMI and the aging-induced decrease in parasympathetic tone activity.

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“…Minor ECG changes do not necessarily prevent a subject from being included in an echo reference material (2). Moreover, previous studies in which healthy adults have been screened with Holter ECGs have revealed that arrhythmias are common in the elderly population (3)(4)(5)(6)(7). Although most of the changes have been considered as benign, other studies have shown that a minor change in ECG also increases the risk of having more severe heart complications in later life (8)(9)(10)(11).…”

Section: Introductionmentioning

confidence: 99%

Are ECG changes in heart-healthy individuals of various ages related to cardiac disease 20 years later?

Erelund

Karp

Wiklund

et al. 2021

ujms

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Background: This research study aimed at assessing the electrocardiographic (ECG) changes caused by ageing in a cohort of healthy subjects with normal echocardiographic examinations. Methods: A total of 219 healthy individuals (119 males and 100 females) were evaluated for possible arrhythmias with a standard 12-lead resting ECG and 24-h Holter ECG. As the recordings were performed between 1998 and 2000, a 20-year follow-up study was carried out by assessing the local medical records to investigate whether the subjects had experienced any cardiovascular health complications or disease since the baseline assessment. Results: Eighty-three subjects (45 males and 38 females) presented with pathological ECG findings at baseline. The most common finding on analysis of Holter ECG recordings was premature atrial contractions, and the most severe pathological finding was episodes of ventricular tachycardia (eight subjects). Regarding the analysis of the standard 12-lead ECG, the most common finding was left ventricular hypertrophy, and the most severe pathological findings were ST-T changes and prolongation of the QT interval. Despite other cardiac examinations performed on these patients showing normal results, in combination with a strict inclusion criterion, this study showed that 28% of all subjects had pathological resting 12-lead ECGs at rest and 35% had pathological heart rhythms when assessed by 24-h Holter ECG. At follow-up, 21% of females and 43% of males had presented with ECG abnormalities, and 30% of females and 36% of males had cardiovascular disease. There was hypertension in 45% of females and in 58% of males. However, no association was found between the follow-up findings and ECG changes seen at baseline. Conclusion: Although most ECG changes found at baseline could be considered as a normal variation, they may progress to more severe heart complications as the subject ages. The results of this study also validate ECG findings of previous studies and underline that diagnostic criteria should be based on gender and age.

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Twenty-Four-Hour Electrocardiography in a Healthy Elderly Population

Cited by 7 publications

References 11 publications

Aetiological Pattern of Premature Ventricular and Atrial Complexes and their Consequence on Morbidity and Mortality

Aetiological Pattern of Premature Ventricular and Atrial Complexes and their Consequence on Morbidity and Mortality

Age-related reference intervals for ambulatory electrocardiographic parameters in healthy individuals

Are ECG changes in heart-healthy individuals of various ages related to cardiac disease 20 years later?

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