Twenty Years of Plaque Incision and Grafting for Peyronie’s Disease: A Review of Literature

Rice, Patrick; Somani, Bhaskar K.; Rees, Rowland

doi:10.1016/j.esxm.2019.01.001

Cited by 29 publications

(20 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…When erectile dysfunction exists, penile prosthesis implantation is required, which is out of the scope of this article 2 . Reconstruction techniques are advised when the erectile function is satisfactory (with or without medication) 11 . These techniques include plication and grafting methods (first shortens the convex aspect, latter elongates the concave side).…”

Section: Discussionmentioning

confidence: 99%

Saphenous Vein Graft for Treatment of Peyronie’s Disease, a Comparison between Single and Multiple Graft Reconstruction

Tabassi

Mottaghi²,

Nekooei³

et al. 2022

WJPS

View full text Add to dashboard Cite

Background: Surgical reconstruction is the gold standard of treatment for Peyronie's disease (PD). Grafting procedures provide satisfactory outcomes in patients with complex curvature, short penile length, and without previous erectile dysfunction (ED). We aimed to compare two different grafting methods of reconstruction in patients with PD.Method: Fifty-two PD patients at Imam-Reza hospital of Mashhad from October 2011 to January 2019 with stable plaque, penile angulation of >60˚, complex curvature, and without ED who consented to cooperate, included in our study and divided into two groups. The first group consists of 26 patients, undergone grafting through a double-Y incision and a single saphenous graft placed within the incision. For the second group, two smaller saphenous vein grafts were placed in the two parallel incisions. ED assessed pre-and postoperational via the International index of erectile function. Penile angulation less than 20 degrees was considered a favorable outcome. Patients followed for 18 months, and sacculation, penile shortening, post-operation infection, and penile hypoesthesia were assessed as complications. We used a paired t-test to compare these two groups.Results: ED was 25% and 12% in the first and the second group, respectively. Statistics showed no difference between the two groups regarding pre and post-operational ED (P=0.1). Regarding complications during follow-up, sacculation occurred in four patients of the first group and none of the second group patients but no significant difference (P=0.23). Conclusion:We found no superiority to declare between these two procedures, although regarding the small sample size of our study, further evaluations are needed to establish more reliable results.

show abstract

Section: Discussionmentioning

confidence: 99%

Saphenous Vein Graft for Treatment of Peyronie’s Disease, a Comparison between Single and Multiple Graft Reconstruction

Tabassi

Mottaghi²,

Nekooei³

et al. 2022

WJPS

View full text Add to dashboard Cite

show abstract

“…22,35,70 No TA incision type has proven to be superior over others. 71 A variety of grafts are now available to the reconstructive surgeon, including autologous grafts, allografts, synthetic grafts and xenografts. The distribution of graft materials based on the reviewed evidence is summarized in…”

Section: Evidencementioning

confidence: 99%

ESSM Position Statement on Surgical Treatment of Peyronie's Disease

et al. 2021

View full text Add to dashboard Cite

Introduction Patients with Peyronie's disease may experience significat distress. The choice of treatment depends on a variety of factors, including the stage of the disease, the presence of pain, severity and direction of the curvature, penile length and the quality of erectile function. Aim To review the evidence associated with surgical treatment of Peyronie‘s Disease and provide clinical recommendations on behalf of the European Society for Sexual Medicine. 131 peer-reviewed studies and systematic reviews, which were published from 2009 to 2019 in the English language, were included. Methods MEDLINE, Google Scholar and EMBASE were searched for randomized clinical trials, meta-analyses, open-label prospective and retrospective studies. Main Outcome Measure The panel provided statements on clinically relevant questions including patient involvement in the decision process, indications for surgery, choice of the approach, and the management of patient expectations. A comparison of the different grafts used in patients who have undergone plaque incision/excision and grafting in order to identify an ideal graft, has been carried out. The prevalence of postoperative complications has been summarized. Levels of evidence were provided according to the Oxford 2011 criteria and Oxford Centre for Evidence-Based Medicine recommendations. Results In order to allow shared decision making, a patient preoperative counselling regarding the pros and cons of each intervention is recommended. In particular, adverse effects of surgical treatments should be discussed to set realistic understanding and expectations of surgical outcomes and ultimately improve postoperative satisfaction rates. Surgical treatment should be only offered in the chronic phase of the condition, when the deformity and/or degree of erectile dysfunction, prevent patients from engaging in satisfying sexual interaction, or if the deformity is the cause of severe bother. Conclusions Current European Society for Sexual Medicine recommendations cover several aspects of Peyronie's disease treatment. These recommendations aim both to ensure patients and partners have accurate and realistic expectations of their treatment options, as well as to formulate algorithms to guide clinician management pathways. Osmonov D, Ragheb A, Ward S et al, ESSM Position Statement on Surgical Treatment of Peyronie's Disease. Sex Med 2022;10:100459.

show abstract

“…Patient satisfaction rates, which take into account not only straightness, but also other aspects, such as postoperative penile length and erectile function, are similarly variable, ranging from 60 to 100% 35 . Postoperative complications that compromise patient satisfaction include perceived penile shortening (0–90%) and penile sensory changes (0–22%) 35,118,122 . Sensory changes are transient in the majority of patients, and a recent report from Terrier et al.…”

Section: Surgerymentioning

confidence: 99%

“…Sensory changes are transient in the majority of patients, and a recent report from Terrier et al. found that, although 20% of men experienced some degree of glans hypoesthesia at 1 month after grafting, just 3% had persistent deficits at 12 months postoperatively 122,123 . Subjective and objective penile length loss can also be allayed by postoperative penile rehabilitation with PTT or VT 17,124 …”

Section: Surgerymentioning

confidence: 99%

Peyronie’s disease: Contemporary evaluation and management

2020

View full text Add to dashboard Cite

Peyronie's disease is a common yet poorly understood condition characterized by penile pain, curvature, sexual dysfunction and psychological bother. Peyronie's disease represents a penile wound healing disorder, and is thought to arise from exuberant scarring in response to penile trauma in genetically predisposed men. In the absence of active treatment, the majority of men experience stable or worsening symptoms, with few reporting spontaneous resolution in penile curvature or other deformity. In contrast, penile pain improves or resolves in the majority of men. Treatment options vary based on symptom severity and stability. Several oral therapies are commonly prescribed, although to date there are no strong data to support any oral agents as monotherapy for Peyronie's disease. Other options including penile traction therapy and intralesional injections result in modest improvements for many patients, particularly when used early after symptom onset. Penile straightening through approaches, such as penile plication and plaque incision or partial excision and grafting, represent the most rapid and reliable approach to correct penile curvature once the symptoms have stabilized. Side-effects vary based on the type of surgery carried out, and include penile shortening, sensation changes and erectile dysfunction in the minority of men. In patients with drug refractory erectile dysfunction and Peyronie's disease, placement of a penile prosthesis will address both issues, and is associated with high levels of patient satisfaction. The current review provides a practical approach to the modern evaluation and management of patients presenting with Peyronie's disease.

show abstract

Twenty Years of Plaque Incision and Grafting for Peyronie’s Disease: A Review of Literature

Cited by 29 publications

References 43 publications

Saphenous Vein Graft for Treatment of Peyronie’s Disease, a Comparison between Single and Multiple Graft Reconstruction

Saphenous Vein Graft for Treatment of Peyronie’s Disease, a Comparison between Single and Multiple Graft Reconstruction

ESSM Position Statement on Surgical Treatment of Peyronie's Disease

Peyronie’s disease: Contemporary evaluation and management

Contact Info

Product

Resources

About