Twenty years of supramolecular solvents in sample preparation for chromatography: achievements and challenges ahead

Rubio, Soledad

doi:10.1007/s00216-020-02559-y

Cited by 74 publications

(20 citation statements)

References 130 publications

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“…Nevertheless, sample pretreatment is a key step for the detection of BPA, but most sample preparations are time-consuming and labour-intensive [7] . Since 2000, sample pretreatment methods have undergone considerable development, also due to the use of nano-structured liquids, named supramolecular solvents that combine extraction and clean-up in a single stage [8 , 9] , and due to selective sorbents, such as molecularly imprinted polymers (MIPs), which are synthetic tailor-made separation polymers having a predetermined selectivity for a given analyte, or group of structurally related compounds. MIPs are obtained by polymerizing functional and cross-linking monomers around a template molecule, leading to a highly cross-linked three-dimensional network polymer [10 , 11] .…”

Section: Methods Detailsmentioning

confidence: 99%

A rapid analysis of Bisphenol A using MISPE coupled with HPLC-FLD in tissues of food-producing animals

Cerkvenik-Flajs

Šturm

2021

MethodsX

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Bisphenol A (BPA) is a highly-produced organic compound of anthropogenic origin with a wide-range use and is ubiquitously present in both living organisms and the environment. A previously published analytical method for testing of the free (aglycone) BPA in foodstuffs was simplified and optimized for sheep muscle tissue, kidney and liver, by using only a single MISPE purification step allied with HPLC-FLD analysis. The recovery rates and RSD values over a concentration range of 1–10 µg/kg were in the range of 67‒86% and 3‒34%, respectively, while linearity in the matrix, represented by the r 2 , was ≥0.999. LOD values were 0.5‒1 µg/kg and LOQ values were 1 µg/kg. The analytical method used is a contribution to the field of veterinary toxicology and food testing and also proved to be applicable for other food-producing animal species, e.g. pigs, poultry and freshwater fish. The MISPE sorbent material for testing of BPA was reusable, with up to five re-use cycles without significant loss in performance characteristics. The paper reports on a rapid determination of free (aglycone) BPA in tissues of food-producing animals by HPLC-FLD and presents a substantial improvement of analytical performance with regard to time- and cost-savings, as well as environmental protection. MISPE is an advanced analytical technology, and the results proved that in a single and simplified SPE step it had good performance characteristics such as selectivity, recovery and precision, allied with low LOD and LOQ values. It was proved that MISPE BPA cartridges could be used at least five times without significant loss of methodological recovery and precision.

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Section: Methods Detailsmentioning

confidence: 99%

A rapid analysis of Bisphenol A using MISPE coupled with HPLC-FLD in tissues of food-producing animals

Cerkvenik-Flajs

Šturm

2021

MethodsX

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“…On the one hand, for ionic amphiphiles, a neutralization of the charge driven by the addition of a counterion, or a change of the pH will reduce the electrostatic repulsion. On the other hand, for non-ionic SUPRAs, the addition of an organic solvent to produce the desolvation of the hydrophilic heads is the most usual approach [40].…”

Section: Supramolecular Solventsmentioning

confidence: 99%

“…These SUPRAs possess exceptional extraction capabilities due to their great surface and their different polarity environments. Moreover, they can be synthesized in situ during the analysis and they do not need extra treatment to be introduced in LC systems (as it happens with ILs) [40], making them really attractive for microextraction approaches.…”

Section: Supramolecular Solventsmentioning

confidence: 99%

Use of green alternative solvents in dispersive liquid‐liquid microextraction: A review

Grau

Azorín

Benedé

et al. 2021

J of Separation Science

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Dispersive liquid-liquid microextraction is one of the most widely used microextraction techniques currently in the Analytical Chemistry field, mainly due to its simplicity and rapidity. The operational mode of this approach has been constantly changing since its introduction, adapting to new trends and applications.Most of these changes are related to the nature of the solvent employed for the microextraction. From the classical halogenated solvents (e.g., chloroform or dichloromethane), different alternatives have been proposed in order to obtain safer and non-pollutants microextraction applications. In this sense, low density solvents, such as alkanols, switchable hydrophobicity solvents and ionic liquids were the first and most popular replacements for halogenated solvents, which provided similar or better results than these classical dispersive liquid-liquid microextraction solvents.However, despite the good performances obtained with low density solvents and

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“…SUPRASs are nanostructured liquids produced in colloidal suspensions of amphiphiles, by a self-assembly and coacervation phenomenon [52,53]. These solvents are characterized by presenting different polarity microenvironments, multiple binding sites, while having the possibility of tailoring their properties.…”

Section: Supras-based Ffsmentioning

confidence: 99%

“…Their preparation is divided into two steps: (i) preparation of a colloidal suspension above the critical aggregation concentration, and (ii) modification of the environmental conditions by introducing a coacervation-inducing agent to increase the size of the aggregates, thus forming droplets with different densities. This leads to the formation of a new liquid phase where the droplets are kept as individual entities [52,54]. Although the greenness and outstanding properties of these solvents, their use is still being not widely extended.…”

Section: Supras-based Ffsmentioning

confidence: 99%

The Use of Ferrofluids in Analytical Sample Preparation: A Review

2021

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Ferrofluids (FFs) constitute a type of tunable magnetic material, formed by magnetic nanoparticles suspended in a liquid carrier. The astonishing magnetic properties of these materials and their liquid nature have led to their extended use in different applications, including fields such as magnetochemistry, optics, and biomedicine, among others. Recently, FFs have been incorporated as extractant materials in magnetic-driven analytical sample preparation procedures, thus, permitting the development of different applications. FF-based extraction takes advantage of both the magnetic susceptibility of the nanoparticles and the properties of the liquid carrier, which are responsible for a wide variety of interactions with analytes and ultimately are a key factor in achieving better extraction performance. This review article classifies existing FFs in terms of the solvent used as a carrier (organic solvents, water, ionic liquids, deep eutectic solvents, and supramolecular solvents) while overviewing the most relevant analytical applications in the last decade.

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Twenty years of supramolecular solvents in sample preparation for chromatography: achievements and challenges ahead

Cited by 74 publications

References 130 publications

A rapid analysis of Bisphenol A using MISPE coupled with HPLC-FLD in tissues of food-producing animals

A rapid analysis of Bisphenol A using MISPE coupled with HPLC-FLD in tissues of food-producing animals

Use of green alternative solvents in dispersive liquid‐liquid microextraction: A review

The Use of Ferrofluids in Analytical Sample Preparation: A Review

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