Twins reared apart provide a fascinating experiment to distinguish genetic from environmental influences. However, there is as yet no broad report on distribution of twins reared apart, especially in the Chinese population. In this study, information on 18,295 volunteer twin pairs of all age groups was compiled in nine provinces or cities of China, and questionnaires were used for zygosity determination. It was discovered that twins reared apart from 0 to 10 years of age accounted for 2.2% of all twin interviewees, with the proportion of this 0-10 group separated before 1, 2, and 5 years old, accounting for 65.3%, 76.1%, and 91.3%, respectively. The proportion of twins reared apart is not significantly related to zygosity or gender, but it is related to region and twin age. As the age of twins lowers, the proportion of those reared apart gradually decreases. Twins reared apart will become rarer in the future and therefore should be cherished as a resource.Keywords: twin studies, child rearing, adoption, environment, genes Classical twin design (CTD) estimates the parameters of additive genetic variance (V A ), non-additive genetic variance (V NA ), common environmental effect variance (V C ), and unique environmental effect variance (V E ) by comparing the similarities between monozygotic (MZ) twins and dizygotic (DZ) twins. Apart from these four parameters, the correlation coefficient (r) of DZ twins attributable to non-additive genetic influence is also unidentified (Coventry & Keller, 2005). However, CTD only obtains three observations: total phenotypic variance, MZ phenotypic covariance, and DZ phenotypic covariance. It is obviously impossible to deduce the five parameters from the three observations, since the degree of freedom will be negative when using structural equation models (Ozaki et al., 2011). We therefore must assume r = 1/4 and V C or V NA = 0 to estimate the three other parameters. This is a potential limitation of CTD -bias -and often occurs during parameter estimation since V C and V NA cannot be estimated simultaneously while fixing r at 1/4 (Coventry & Keller, 2005).One way to address the problem is to study twins reared apart, which is an ingenious concept and known as 'the fascinating experiment of nature, the simplest and most powerful method for disentangling the influence of