We review various superspace approaches to the description of the low-energy effective action in N = 4 super Yang-Mills (SYM) theory. We consider the four-derivative part of the low-energy effective action in the Coulomb branch. The typical components of this effective action are the gauge field F 4 /X 4 and the scalar field Wess-Zumino terms. We construct N = 4 supersymmetric completions of these terms in the framework of different harmonic superspaces supporting N = 2, 3, 4 supersymmetries. These approaches are complementary to each other in the sense that they make manifest different subgroups of the total SU(4) R-symmetry group. We show that the effective action acquires an extremely simple form in those superspaces which manifest the non-anomalous maximal subgroups of SU(4). The common characteristic feature of our construction is that we restore the superfield effective actions exclusively by employing the N = 4 supersymmetry and/or superconformal P SU(2, 2|4) symmetry.