Two Adults With Multisystem Inflammatory Syndrome Post-COVID-19 in a Lebanese Hospital: A Case Report

Abstract

COVID-19 is a respiratory illness with multiple extra-pulmonary complications. The multisystem inflammatory syndrome (MIS) is one of its complications that usually affects children and is known as MIS-C, but several cases have been reported in adults, symbolized by MIS-A. Thus, the Centers for Disease Control and Prevention (CDC) developed a working case definition of MIS-A, which includes several criteria. Here we report two cases of adult male patients with clinical and laboratory symptoms consistent with MIS-A. Case one patient presented at a late stage after two weeks post the onset of symptoms. His health deteriorated rapidly, and eventually, he passed away. However, the second patient presented a few days after the symptoms’ onset and took a course of steroids. He was discharged home.

Multisystem inflammatory syndrome in adults: Characteristics, treatment, and outcomes

“…F I G U R E 1 Geographical distribution of reported cases of multisystem inflammatory syndrome in adults (as of October 26, 2022) 16,[27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43] The first reported MIS-A case was a 45-year-old male who developed fever for more than 5 days, erythema multiforme-like rash, bilateral nonexudative conjunctivitis, erythema or cracking of the lips, and unilateral cervical lymphadenopathy after caring for his wife with SARS-CoV-2 infection 2 weeks earlier. 25 He had no significant past medical history and denied respiratory symptoms on presentation.…”

“…Geographical distribution of reported cases of multisystem inflammatory syndrome in adults (as of October 26, 2022) 16,27–43 …”

“…[15][16][17]19,25,26 Many countries, including the United States, the UK, Italy, Israel, India, Canada, Japan, Pakistan, the United Arab Emirates, Croatia, Norway, France, Spain, Belgium, Portugal, South Africa, Lebanon, Switzerland, Thailand, Turkey, Austria, Cyprus, Sweden, Qatar, Oman, Brazil, South Korea, Germany, Uruguay, Mexico, Ireland, Malaysia, Australia, and Taiwan had reported the occurrence of MIS-A (Figure 1). 16,[27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43] To help understand this rare but fatal complication, this review was conducted to provide updated and comprehensive information on MIS-A.…”