Two Cases of Calcaneal Osteosarcomas Presenting as Aneurysmal Bone Cysts

Leithner, Andreas; Bodó, Koppany; Scheipl, Susanne; Radl, Roman; Kastner, Norbert; Windhager, Reinhard

doi:10.1177/107110070402501111

Cited by 14 publications

(10 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Based on previous data, the mean time interval between onset of symptoms and correct diagnosis is usually more than one year [5,12,13,21]. Case reports of missed osteosarcoma of the calcaneus have been reported [5,12]. The results of our study appear to be consistent with previous data [25,26].…”

Section: Discussionsupporting

confidence: 83%

“…Even histological examination seems to be limited sometimes, because it does not routinely reveal the correct diagnosis. Several factors may contribute to this, since in contrast to other locations differing biological behaviour of calcaneal osteosarcoma has been noted before [2,3,12,13,24]. Some authors suggest that osteosarcoma of the foot may represent a distinct subgroup with clinical features that differ highly from conventional osteosarcoma [5,22].…”

Section: Discussionmentioning

confidence: 98%

“…Thus, inadequate therapy is instituted. Based on previous data, the mean time interval between onset of symptoms and correct diagnosis is usually more than one year [5,12,13,21]. Case reports of missed osteosarcoma of the calcaneus have been reported [5,12].…”

Section: Discussionmentioning

confidence: 99%

“…Concerning the calcaneal bone many authors favour below knee amputation [1,5,[21][22][23] after major resection of malignant tumours. While limb salvage for osteosarcoma of long bones is accepted as state-ofthe-art treatment, it can rarely be applied for malignant tumours of the calcaneus, due to loss of function [12]. Limb salvage of primary malignant calcaneal tumours is sometimes performed for stage I (low-grade) and stage IIA (high-grade, intracompartmental) lesions according to Enneking [8,9].…”

Section: Discussionmentioning

confidence: 99%

“…Intraosseous lipomas were additionally re-examined according to Milgram's classification [10,11]. Nineteen patients had been included in previous studies [12][13][14].…”

Section: Methodsmentioning

confidence: 99%

See 4 more Smart Citations

Osteolytic lesions of the calcaneus: results from a multicentre study

Weger

Фрингс

Friesenbichler

et al. 2013

International Orthopaedics (SICOT)

Self Cite

View full text Add to dashboard Cite

Purpose Tumours of the calcaneus are exceedingly rare and the correct diagnosis is often missed. X-rays are the standard clinical examination tool and therefore we wanted to discover whether X-rays alone were a sufficient diagnostic tool for these tumours. Diard's classification was applied to define whether different types of lesions were characteristically distributed in the bone and in addition we analysed whether type and/or duration of symptoms were possible indicators of malignancy. Methods Ninety-two patients' files (59 men and 33 women) were retrospectively reviewed. Seventy-five patients with a mean age at surgery of 28 years (range five to 78) were surgically treated. Parameters analysed were sex, age at surgery, side, type and duration of symptoms, tentative diagnosis, biopsy prior to surgery, operative procedure, recurrence rate, revision and localisation of the lesion according to Diard. For each lesion the first documented radiological diagnosis andin cases of malignancy-Enneking's classification was applied.Results Discrepancies between the radiological and definitive histological diagnosis occurred in 38 (41 %) of 92 cases. In eight (osteosarcoma n =5, Ewing's sarcoma n =2, metastases n =1) of 17 malignant cases radiological examination initially gave no evidence of malignancy, resulting in an unplanned excision ("whoops procedure") in three cases of osteosarcoma. Applying Diard's system trabecular area 6 (radiolucent area) was highly affected in 64 (80 %) of 80 investigated plain Xrays, whereas areas 1 and 5 were affected in nine (11 %) and 16 (20 %) cases only. Conclusions In each case of an osteolytic lesion of the calcaneus a malignant tumour must be ruled out, and thus preoperative plain X-rays in two planes alone are not sufficient and should therefore be followed by magnetic resonance imaging. Applying the Diard system different types of lesions are not characteristically distributed in the bone. Increasing pain for more than ten days without previous trauma should always justify further examinations.

show abstract

Section: Discussionsupporting

confidence: 83%

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…Intraosseous lipomas were additionally re-examined according to Milgram's classification [10,11]. Nineteen patients had been included in previous studies [12][13][14].…”

Section: Methodsmentioning

confidence: 99%

See 3 more Smart Citations

Osteolytic lesions of the calcaneus: results from a multicentre study

Weger

Фрингс

Friesenbichler

et al. 2013

International Orthopaedics (SICOT)

Self Cite

View full text Add to dashboard Cite

show abstract

Diagnoses, treatment, and oncologic outcomes in patients with calcaneal malignances: Case series, systematic literature review, and pooled cohort analysis

Newman

Rein

Theyskens

et al. 2020

Journal of Surgical Oncology

View full text Add to dashboard Cite

Background and Objectives: Malignant tumors of the calcaneus are rare but pose a treatment challenge. Aims: (1) describe the demographics of calcaneal malignancies in a large cohort; (2) describe survival after amputation versus limb-salvage surgery for high-grade tumors. Methods: Study group: a "pooled" cohort of patients with primary calcaneal malignancies treated at two cancer centers (1984−2015) and systematic literature review. Kaplan−Meier analyses described survival across treatment and diagnostic groups; proportional hazards modeling assessed mortality after amputation versus limb salvage. Results: A total of 131 patients (11 treated at our centers and 120 patients from 53 published studies) with a median 36-month follow-up were included. Diagnoses included Ewing sarcoma (41%), osteosarcoma (30%), and chondrosarcoma (17%); 5-year survival rates were 43%, 73% (70%, high grade only), and 84% (60%, high grade only), respectively. Treatment involved amputation in 52%, limb salvage in 27%, and no surgery in 21%. There was no difference in mortality following limb salvage surgery (vs. amputation) for high-grade tumors (HR 0.38; 95% CI 0.14−1.05), after adjusting for Ewing sarcoma diagnosis (HR 5.15; 95% CI 1.55−17.14), metastatic disease at diagnosis (HR 3.88; 95% CI 1.29−11.64), and age (per-year HR 1.04; 95% CI 1.02−1.07). Conclusions: Limb salvage is oncologically-feasible for calcaneal malignancies.

show abstract

First report of a solid variant of aneurysmal bone cyst in the os sacrum

et al. 2009

View full text Add to dashboard Cite

We report on a 19-year-old woman with a rapidly growing, solid variant of aneurysmal bone cyst (solid ABC) in the right part of the lateral mass of the sacrum. On admission, the magnetic resonance imaging (MRI) scan disclosed an inhomogeneous low intensity mass right of the centre of the os sacrum with a diameter of 38 x 64 mm and a height of 56 mm on T1 and T2 weighted images. The mass showed homogenous high signal intensity on Gd-enhanced images. Computed tomography demonstrated an expansile osteolytic lesion and (99m)Tc-methylene diphosphonate bone scintigraphy revealed uniform accumulation in the lesion. The histological evaluation showed a proliferation of fibroblasts, histiocytes, chronic inflammatory cells and numerous multinucleated giant cells. Nevertheless, the cells were devoid of nuclear atypia. A cystic component was not observed. In spite of thorough curettage, the patient suffered from recurrence and severe neurological deficits. A review of the literature revealed no previous cases of solid ABC in the sacrum.

show abstract

Two Cases of Calcaneal Osteosarcomas Presenting as Aneurysmal Bone Cysts

Abstract: For information on prices and availability of reprints, call 410-494-4994 X226.

Cited by 14 publications

References 14 publications

Osteolytic lesions of the calcaneus: results from a multicentre study

Osteolytic lesions of the calcaneus: results from a multicentre study

Diagnoses, treatment, and oncologic outcomes in patients with calcaneal malignances: Case series, systematic literature review, and pooled cohort analysis

First report of a solid variant of aneurysmal bone cyst in the os sacrum

Contact Info

Product

Resources

About