Two Cases of Giant Basal Cell Carcinoma of the Vulva

Basal cell carcinoma on the dorsum of the foot with inguinal and pelvic lymph nodes metastases

“…According to Cotran 2 and Lattes, 4 the diagnostic criteria for metastatic BCC are as follows: (i) the primary tumor is in the skin, not in the mucous membrane; (ii) metastasis occurs at a site distant from the primary lesion and local extensions or far‐flung implantations are excluded; and (iii) the primary and metastatic lesions must have the same histology without any squamous cell carcinoma components. Approximately 300 cases of metastatic BCC have been described 5–8 in the English literature, and 27 cases have been reported in Japanese literature 9–30 . To discover any characteristic features of metastatic BCC, we compared 27 Japanese cases of metastatic BCC with 137 cases of non‐metastatic BCC treated in our hospital between 2007 and 2009 (Table 1).…”