2022
DOI: 10.21608/ajps.2022.223770
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Two Different Chromatographic Methods for Simultaneous Determination of Common Cold Drugs Ambroxol Hydrochloride, Pseudoephedrine Hydrochloride, Levoceterizine Dihydrochloride and Desloratadine, in Pure Forms, and in Pharmaceutical Dosage Forms.

Abstract: Two chromatographic methods were developed for simultaneous determination of some drugs used in common cold. First method is TLC-Densitometric method for the simultaneous estimation of Ambroxol hydrochloride (AMB), Pseudoephedrine hydrochloride (PSE) and Desloratadine (DES) in pure form and in pharmaceutical dosage form, the best resolution was obtained by the use of mobile phase (Ethyl acetate: methanol: ammonia), (14: 0.8: 0.5, v/v/v), the scanning of spots was performed at 254 nm in concentration range (1-4… Show more

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