Two dimensional global longitudinal strain of right ventricle using transthoracic echocardiography can detect right ventricular fibrosis confirmed by 320 slice CT in pulmonary hypertension

Ozawa, Koya; Funabashi, Nobusada; Tanabe, Nobuhiro; Yanagawa, Noriyuki; Kataoka, Akihisa; Kobayashi, Yoshio

doi:10.1016/j.ijcard.2013.12.149

Cited by 10 publications

(1 citation statement)

References 10 publications

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“…Right ventricular dyssynchrony is related to a segmental wall stress heterogeneity that also is related to a different RV remodeling phases . An acute RV afterload reduction with inhaled iloprost could lead to a different degrees of homogenization of RV contraction, depending on the state of RV remodeling and fibrosis, and these changes are evaluable by echocardiographic deformation tools …”

Section: Discussionmentioning

confidence: 99%

Acute effect of iloprost inhalation on right atrial function and ventricular dyssynchrony in patients with pulmonary artery hypertension

et al. 2016

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Cambios agudos en la función auricular derecha post uso de iloprost inhalatorio en pacientes con hipertensión arterial pulmonar: estudio con técnicas de deformación de imagen Recibido el 29 de junio de 2015 / Aceptado 30 de julio de 2015 Introducción: El efecto de prostanoides inhalato-rios sobre la función auricular derecha (AD) en hiper-tensión arterial idiopática (HAP) no ha sido estudiado. Objetivo: Evaluar cambios agudos en la función AD y función diastólica del ventrículo derecho en pacientes con HAP post uso de Iloprost inhalatorio. Métodos: Se incluyeron pacientes con HAP sin uso previo de prostanoides. Se realizó un ecocardiograma transtorácico basal y 30 min posterior a la inhalación de iloprost. Se midió dimensión AD, relación E/e´ye´y strain de la AD por speckle tracking, registrando la onda ne-gativa de contracción auricular (SaAD) y la onda posi-tiva de la fase de reservorio (SsAD). Se midió el tiempo de inicio de la fase de reservorio AD durante el sístole ventricular. Resultados: Se estudiaron 16 pacientes (15 muje-res), con edad promedio 44 ± 7,8 años. Post Iloprost disminuyó el volumen AD Conclusión: Con Iloprost inhalatorio en pacientes con HAP se observa una reducción aguda en el tama-ño de la AD y en las presiones de llenado del VD. La deformación durante la fase de reservorio de la AD au-menta y se inicia significativamente antes. Esto sugiere que el Iloprost podría mejorar en forma aguda el trabajo mecánico de la AD en paciente con HAP.

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Section: Discussionmentioning

confidence: 99%

Acute effect of iloprost inhalation on right atrial function and ventricular dyssynchrony in patients with pulmonary artery hypertension

et al. 2016

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Diagnostic and prognostic value of right ventricular strain in patients with pulmonary arterial hypertension and relatively preserved functional capacity studied with echocardiography and magnetic resonance

Costa

Ota-Arakaki

Ramos

et al. 2016

Int J Cardiovasc Imaging

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Right ventricular (RV) dysfunction harbingers adverse prognosis in pulmonary arterial hypertension (PAH). Although conventional two-dimensional echocardiography (2DE) is limited for RV systolic function quantitation, RV strain can be a useful tool. The diagnostic and prognostic impact of 2DE speckle-tracking RV longitudinal strain was evaluated, including other 2DE systolic indexes, in a group of PAH patients without severe impairment of functional capacity, chronic pulmonary thromboembolism or left ventricular dysfunction. Sixty-six group I PAH patients, 67 % NYHA functional class I or II (none in IV) were studied by 2DE to obtain: RV fractional area change, tricuspid annular plane systolic excursion, RV myocardial performance index, tissue Doppler tricuspid annulus systolic velocity. Global, free wall (RVFreeWSt) and septal RV longitudinal systolic strain were obtained. RV ejection fraction by cardiac magnetic resonance (CMR-RVEF) was also assessed. All patients were followed up to 3.9 years (mean 3.3 years). Combined endpoints were hospitalization for worsening PAH or cardiovascular death. Among all the 2DE indexes of RV systolic function, RVFreeWSt exhibited the best correlation with CMR-RVEF (r = 0.83; p < 0.005). Combined endpoints occurred in 15 (22.7 %) patients (6 hospitalizations and 9 deaths). Multivariate analysis identified RVFreeWSt ≤-14 % as the only 2DE independent variable associated with combined endpoints [HR 4.66 (1.25-17.37); p < 0.05]. We conclude that RVFreeWSt may be a suitable non-geometric 2DE surrogate of CMR-RVEF in PAH patients, constituting a powerful independent predictor of long-term outcome in this cohort with relatively preserved functional capacity.

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Massive myocardial aneurysm due to inferior to posterior myocardial infarction complicated with right-sided heart failure in a 36-year-old male

Ono

Funabashi

Takaoka

et al. 2016

International Journal of Cardiology

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Two dimensional global longitudinal strain of right ventricle using transthoracic echocardiography can detect right ventricular fibrosis confirmed by 320 slice CT in pulmonary hypertension

Cited by 10 publications

References 10 publications

Acute effect of iloprost inhalation on right atrial function and ventricular dyssynchrony in patients with pulmonary artery hypertension

Acute effect of iloprost inhalation on right atrial function and ventricular dyssynchrony in patients with pulmonary artery hypertension

Diagnostic and prognostic value of right ventricular strain in patients with pulmonary arterial hypertension and relatively preserved functional capacity studied with echocardiography and magnetic resonance

Massive myocardial aneurysm due to inferior to posterior myocardial infarction complicated with right-sided heart failure in a 36-year-old male

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