Two Neonates With Postnatally Acquired Tickborne Infections

Lyme disease in a neonate complicated by the Jarisch–Herxheimer reaction

“…Handel and colleagues described a case of a 5-week-old infant who presented with fever and several erythema migrans lesions, and whose serology was nonreactive. 5 This patient received a 14-day course of ceftriaxone, with resolution of symptoms. Based on these reports, newborns with findings consistent with early localized disease may also be at higher risk for disseminated disease.…”

Tick-Borne-Associated Illnesses in the Pediatric Intensive Care Unit

“…9,10 Expansion of this disease has been recently noted in the Midwest. 9,11 It is transmitted via an Ixodes tick bite infected with Borrelia burgdorferi with an average incubation period of approximately 2 to 3 weeks. 12,13 Life-Threatening Clinical Presentation…”

“…First, the typical erythema chronicum migrans rash and nonspecific symptoms develop, followed by wide hematogenous dissemination resulting in preferential involvement of specific organs, leading to joint pain, neurological complications, Borrelia lymphocytoma or Lyme carditis. 11,[14][15][16] A late manifestation of this disease includes arthritis and acrodermatitis chronica atrophicans. 15 Patients with early Lyme disease may develop Lyme carditis, leading to atrioventricular (AV) heart block, myopericarditis or first, second, or third degree heart block.…”

“…24 There is an increased risk of coinfection with other infections that can be transmitted by Ixodes ticks, particularly babesiosis. 11,16 Empiric antibiotic therapy with doxycycline should be administered. 11,16 Rocky Mountain-Spotted Fever…”

“…11,16 Empiric antibiotic therapy with doxycycline should be administered. 11,16 Rocky Mountain-Spotted Fever…”